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Biomedical subjects

C Cavalli

Publications and source records attributed to C Cavalli.

32 records · Page 2Linked to original sources
PubMedDate not supplied

Preliminary report on activity and tolerability of epomediol, administered by intravenous infusion, in patients with chronic hepatopathies.

The therapeutic activity and tolerability of epomediol were studied in 28 patients with chronic hepatopathies. Treatment was continued, parenterally, for 10 days (400-600 mg once daily by intravenous infusion). Clinical parameters (headache, right hypochondrial pain, bitter taste in the mouth, asthenia and nausea) and hepatic function (transaminase, alkaline phosphatase and gamma-glutamyl transpeptidase) showed significant improvements. Clinical and systemic tolerabilities of epomediol were satisfactory.

Adult↗
PubMedDate not supplied

[Persistent supraventricular tachycardia in childhood].

Persistent or chronic supraventricular tachycardia is defined as the one occurring in more than 10% of cardiac rhythm during 24 hours. It may begin at any age, persisting months or years, and frequently it is discovered occasionally because it can be asymptomatic. The persistent supraventricular tachycardia (PSVT) represents 20-30% of all supraventricular tachycardias in pediatric age. The two main forms of PSVT are: atrial ectopic tachycardia, and persistent junctional reciprocating tachycardia (PJRT). The authors present 9 cases of children affected by PJRT seen from 1972 to 1985. They discuss the clinical course (mean follow up = 9.5 years), the pharmacologic treatment, the results obtained. They underline the particular resistance to conventional antiarrhythmic therapy of this form. On the other hand an antiarrhythmic treatment is recommended to avoid the risk of congestive heart failure. Nevertheless the prognosis is considered benign because in the majority of cases this type of arrhythmia disappears later on.

Child↗
PubMedDate not supplied

[Dilated cardiomyopathy due to primary carnitine deficiency].

A case of a 3 and a half years old girl with severe congestive heart failure, and typical picture of dilated cardiomyopathy is presented. The serum level of carnitine (17.2 micromoles/l, versus 44.1 +/- 12.2 micromoles/l, normal value for age) and the histologic and biochemical evaluation of quadriceps muscle tissue confirmed the diagnosis of primary deficit of carnitine. L-carnitine (2 gr. three times a day p.o.) was added to anti-congestive therapy. After 8 weeks of therapy, the general and cardiocirculatory conditions are much improved. The physiopathology of dilated cardiomyopathy due to deficit of carnitine are discussed. An early diagnosis, and an early substitutive therapy with L-carnitine dramatically improve the outcome of the disease.

Biopsy↗
PubMedDate not supplied

[Dermatitis herpetiformis and latent celiac disease in two siblings].

The association between coeliac disease (CD) and dermatitis herpetiformis (DH) is well known. Moreover, this cutaneous disease may be the only sign of an otherwise asymptomatic CD. Subjects presenting with both CD and DH generally show an HLA pattern in which A1, B8, DR2, DR7, DQw2 are the most frequent antigens one can find. We report about 2 brothers presenting with DH, clinically asymptomatic, without antigliadin serum antibodies (AGA), but positive to the research of antiendomysial (EMA) ones. The biopsy performed by digestive endoscopy showed a complete atrophy of duodenal villi and the diagnosis of CD was confirmed according to the European Society for Pediatric Gastroenterology and Nutrition (ESPGAN) criteria. The diet without gluten caused the DH to recovery and the duodenal villi microscopic aspect to normalize as well. Both the brothers had the same HLA pattern: A1, B8, DR3-DR2, DQw2. Our clinical study suggests that it is very important, especially for the general practitioner, to recognize a DH and in every child presenting with a dermatitis like that it will be mandatory to perform a laboratory research of both AGA and EMA.

Adolescent↗
PubMedDate not supplied

[Heart transplant: an emotional storm for the child and his family].

The purpose of the present study was a psychological analysis of the emotional state of a family awaiting heart transplantation. Current practice suggests that such emotional reaction is characterized by mixed and contradictory feelings which require further investigation. Subjects were 5 children waiting for transplant and 5 with previous transplant. Methods were: 1) open interview with children and parents; 2) projective drawing test for children (Corman family test, H.T.P., L.A.D.S., M.U.C.T., K.F.D.); 3) "palinomas" questionnaire which investigates: awareness of the illness, child relation with the food, feelings of competence and control, self-esteem and perception of the self. "Palinomas" was created in Italy by a hospital psychological team in order to give a chance to the child to talk about himself and to maintain control over the situation. The information we obtained by "palinomas" revealed to be very useful to understand the personality of the child through the main areas reported above. Within the limits of an introductory study, results indicate that family needs an active psychological support in order to develop a more positive attitude.

Adolescent↗
PubMedDate not supplied

[Nutrition in the first months of life with a new formula containing maltodextrins and enriched with long-chain fatty acids].

According to the recent acquisition about the biochemical properties of the carbohydrates contained in human milk, the addition of maltodextrins to infant formulas became recommended. We refer about the preliminary data of the first utilization of a new formula (Aptamil 1 "Nuova Formula") in which both maltodextrins and Long Chain Fatty Acids are added. Sixty-seven infants were enrolled to the study for the first 4 months of life. Forty-three of them (64%) completed the study and were grouped as follows: Group 1 = 15 subjects exclusively formula-fed (4F, 11M), Group 2 = 21 infants with mixed feeding (breast + formula), Group 3 = 7 cases in which Aptamil 1 "Nuova Formula" substituted another formula (4F, 3M). Auxologic parameters (weight, length, head circumference) were among the normal standard limits according to the percentile charts of the Boston Children's Medical Center. All infants enjoyed the taste of the milk we tested. The food regimen was changed in 4/67 (6%) infants because of alimentary intolerance suspicion but 2/4 infants were subsequently fed with soya milk formula and with an "hypoallergenic" milk respectively, the other 2 continued with another formula. The weight growth chart in infants of Group 1 tended to bend down a little bit between the 3rd and 4th month, reminding the breast-fed infants behavior. Considering the daily milk volume assumed by the same subjects, we found a statistical difference (p < or = 0.01) between the volumes of milk assumed in the 2nd and the 3rd month of life but from the 3rd to the 4th month there was no statistical difference in daily milk volumes. This resembles the breast-fed infants behavior as well. According to our preliminary results the new milk formula we tested seems a very good substitute when an infant can't be breast-fed for any reason.

Dextrins↗