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Biomedical subjects

C Cefai

Publications and source records attributed to C Cefai.

14 recordsLinked to original sources
PubMed2000

Recurring febrile illness in a slaughterhouse worker.

A slaughterhouse worker presented with fever and a pleuropericardial effusion. Conventional microbiology failed to identify the responsible organism. However, DNA sequencing definitively identified Campylobacter fetus ssp fetus, which is rare in immunocompetent individuals. Prolonged treatment was required to eradicate the infection.

Abattoirs↗
PubMed1993

Cowpox can mimic anthrax.

We report a patient suffering from cowpox infection, in whom the clinical features mimicked those of anthrax. The infection may have been acquired as a result of contact with a rodent.

Adolescent↗
PubMed1992

A comparative study of imipenem versus piperacillin plus gentamicin in the initial management of febrile neutropenic patients with haematological malignancies.

Three-hundred and twelve episodes of fever in 234 neutropenic patients with haematological malignancies were treated empirically with either imipenem or a combination of piperacillin and gentamicin. There were no significant differences in the percentages of patients responding to therapy at either 72 h (59% and 56% of assessable episodes in the imipenem and combination groups respectively) or at the end of treatment (55% and 53% of assessable episodes in the imipenem and combination groups respectively). Patients in the piperacillin plus gentamicin group experienced significantly more renal tubular damage whereas those who received imipenem suffered more nausea or vomiting. We conclude that imipenem monotherapy represents an acceptable alternative to piperacillin plus gentamicin as empirical therapy of the febrile neutropenic patient.

Adolescent↗
PubMed1989

A randomised, prospective, single-blind comparison of cefadroxil and amoxycillin in the treatment of acute exacerbations of chronic bronchitis.

Cefadroxil 1 g twice daily and amoxycillin 500 mg three times a day were compared in 111 patients suffering from acute exacerbations of chronic bronchitis. Treatment was for seven days. Excellent or good clinical responses were found in 85 per cent of cases receiving cefadroxil and 81 per cent of patients taking amoxycillin. However, residual symptoms of cough and rhonchi were present to a statistically significantly greater extent in the amoxycillin group. Tolerance of both drugs was good with mild to moderate side effects reported in seven of 54 patients in the cefadroxil group and six of 56 patients taking amoxycillin. Severe nausea and vomiting in two cases in the amoxycillin group resulted in discontinuation of therapy. Microbiological examination of sputum samples showed pathogenic bacteria in 16 per cent, principally Haemophilus influenzae. Amoxycillin 500 mg tds and cefadroxil 1 g bd were equally effective in the treatment of acute exacerbations of chronic bronchitis.

Adolescent↗
PubMed1988

Gastrointestinal carriage rate of Clostridium difficile in elderly, chronic care hospital patients.

The carriage rate of Clostridium difficile in patients at a chronic care hospital was determined by two point prevalence surveys at 6-monthly intervals. In the first survey C. difficile or its toxin was present in stool samples from five symptomless patients on three of the four wards studied. All of these colonized patients had been in hospital for at least 2 months, but there was no relationship between carriage of the organism and antibiotic use. When the survey was repeated 6 months later, no symptomless carriers were found but one symptomatic patient had C. difficile and its toxin present in the stool. The results suggest that C. difficile should always be considered as a possible cause of diarrhoea in long-stay hospitalized patients.

Aged↗