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Biomedical subjects

C Chabaux

Publications and source records attributed to C Chabaux.

10 recordsLinked to original sources

[Internal breast prostheses of silicone: accidents and medico-legal consequences].

The authors gathered the principal information obtained from medical and medicolegal data relating to silicone breast implants. The publications collected and the opinions of various administrative, judiciary and private authorities do not permit at present to determine a complete coherent point of view. The internal silicone breast implants could provoke some inflammatory phenomenons and local sclerosis. The durability and life span of these prostheses is still matter of concern. Though not proved by epidemiological studies the risk of group connective-tissue diseases cannot be definitely dismissed 10 years after the prosthesis implantation, the risk is probably low. Finally the practitioners, especially cancerologists, should continue to use these prostheses. It is to hope that experimental epidemiological research and the progress of manufacturing control allow the use of silicones for medical and chirurgical purposes.

Biocompatible Materials↗

[Occupational allergic dermatoses in the hospital environment].

In Europe, these ten last years, we have seen the HIV epidemic's arrival and the development of the nosocomial diseases with their dangerous consequences, in hospital. The aldehyde use, with strong sensitizing power and great ability of disinfection, involve more and more numerous dermatitis. The increasing use of latex gloves is parallel to the development of different allergic diseases, of which anaphylactic shock may be one of the manifestations.

Allergens↗

[The initiating role of several respiratory and skin contaminants in food allergies].

The authors present data which suggest that mustard hypersensitivity can result from Isocyanates induced occupational asthma. Isothiocyanates present in mustard spice is probably responsible for this cross-sensitivity. Frequently, food allergies result from skin or respiratory primary contact and sensitization. Some examples are proposed. Distinctive structures and functions of immunological system in cutaneous, respiratory and digestive apparatus, give an explanation for the predominance of skin and respiratory immunological systems to promote hypersensitivity. For the prevention of food allergies, it is very important to avoid excessive skin and respiratory contaminations by allergens in the work and home environments.

Adult↗

[Human allergic hypersensitivity and chemical residues in food].

Chemical and immunological basis of hypersensitivity reactions to low molecular weight substances are recalled. Then the authors give examples of directly reactive chemicals as penicillins and some antineoplastic drugs. The possible role of reactive impurities as penicillins and aspirin is also reminded. It is emphazised that some substances induce allergic reactions through their metabolites: such reactions are mostly unforeseeable. The second part of the paper recalls the main clinical manifestations of these allergic hypersensitivity reactions to chemical residues in food. It is finally emphazised that the datas from animal experiments and epidemiological studies could allow a classification of chemical substances according to their potential risk. This would be of great importance to determine which substances may be authorized in food stuffs and/or to specify the maximum allowable concentrations.

Anti-Bacterial Agents↗

[Subcutaneous injection of metallic mercury. Report of 4 cases].

4 cases of subcutaneous injection of metallic mercury are reported and compared with those recorded by others. Subcutaneous injection always causes local inflammatory reaction and granuloma formation. Systematic mercury absorption is the rule as it is proved by high mercury levels in blood and urine. Nevertheless this absorption is usually too small to be responsible for toxic manifestations. Surgical excision of all accessible contaminated subcutaneous areas should be performed. When residual mercury is roentgenographically detectable regular monitoring of CNS, renal function and urinary and/or blood mercury levels are necessary.

Accidents↗

[Silicosis].

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Humans↗