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C Cherubini

Publications and source records attributed to C Cherubini.

5 recordsLinked to original sources
PubMed2006

Heat transfer in Fitzhugh-Nagumo models.

An extended FitzHugh-Nagumo model coupled with dynamical heat transfer in tissue, as described by a bioheat equation, is derived and confronted with experiments. The main outcome of this analysis is that traveling pulses and spiral waves of electric activity produce temperature variations on the order of tens of mu degrees C. In particular, the model predicts that a spiral wave's tip, heating the surrounding medium as a consequence of the Joule effect, leads to characteristic hot spots. This process could possibly be used to have a direct visualization of the tip's position by using thermal detectors.

Action Potentials↗
PubMed2005

Viscoelastic Fitzhugh-Nagumo models.

An extended Fitzhugh-Nagumo model including linear viscoelasticity is derived in general and studied in detail in the one-dimensional case. The equations of the theory are numerically integrated in two situations: (i) a free insulated fiber activated by an initial Gaussian distribution of action potential, and (ii) a clamped fiber stimulated by two counter phased currents, located at both ends of the space domain. The former case accounts for a description of the physiological experiments on biological samples in which a fiber contracts because of the spread of action potential, and then relaxes. The latter case, instead, is introduced to extend recent models discussing a strongly electrically stimulated fiber so that nodal structures associated on quasistanding waves are produced. Results are qualitatively in agreement with physiological behavior of cardiac fibers. Modifications induced on the action potential of a standard Fitzhugh-Nagumo model appear to be very small even when strong external electric stimulations are activated. On the other hand, elastic backreaction is evident in the model.

Action Potentials↗
PubMedDate not supplied

[Epidemiology and prevention in dialysis].

During the last years, prevention of hospital infections assumed the role of primary objective for active interventions and dedicated laws for safety in work areas and for facilities accreditation defined responsibilities and preventive measures to reduce the biological risk. Dialysis centers are areas where the infective risk is high but the strict application of the Universal Measures and of specific recommendations are sufficient to reduce the risk of diffusion and transmission of pathogens. The late referral of the ESRD patient, with or without infectious comorbidity, shows an intervention field, in which a local epidemiological survey gives useful data and stimulates the data management at hospital level (Epidemiologists and nefrologists) and family doctors, to improve the disease management of very complex and high cost patients.

Bacterial Infections↗