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Biomedical subjects

C Chiesi

Publications and source records attributed to C Chiesi.

8 recordsLinked to original sources

Abnormal spatial localization in patients with herpes zoster ophthalmicus. Evidence for the presence of proprioceptive information.

Patients with herpes zoster of the ophthalmic branch of the trigeminal nerve and normal ocular motility were examined. They were asked to point to targets without the sight of their own hand. Significant errors were found on the affected side. Proprioceptive information of the extraocular muscles is assumed to travel in the trigeminal nerve, and these results thus suggest the existence of peripheral afferent signals influencing eye-hand coordination.

Herpes Zoster Ophthalmicus↗

Critical analysis of visual function evaluating techniques in newborn babies.

The most widely-used techniques for testing visual function in babies are reviewed. Advantages and limitations of optokinetic nystagmus testing, visual evoked responses and preferential looking techniques are considered. The theoretical basis and the clinical applicability of those techniques are outlined. Other simple methods are considered as well, which allow practicing ophthalmologists to assess the presence or absence of vision in babies. The importance of early diagnosis for prevention and treatment of visual deficits in babies is stressed.

Evoked Potentials, Visual↗

Binocular visual perception in strabismics studied by means of visual evoked responses.

Ten normal subjects and 14 patients with comitant esotropia were examined by means of pattern visual evoked responses (VER) under monocular and binocular viewing conditions. When both eyes were stimulated together a VER summation was noted both in normals and in strabismics with small-angle deviation and anomalous retinal correspondence (ARC). This is considered as an objective proof of binocularity. Patients with large-angle strabismus and/or suppression of the image of the deviated eye did not show summation. The significance of summation and its relationship with binocular vision was analyzed by recording binocular VER in normals in which diplopia was artificially induced and in strabismics who spontaneously exhibited double vision. A simple way for differentiating normals from strabismics by means of VERs is presented, considering that the presence or absence of summation per se does not achieve this result. This method is based on the anteposition in front of the fixing eye of neutral filters of increasing density. Summation disappears in strabismics with much weaker filters than in normals (0.5 versus 1.6 log. unit).

Electrophysiology↗

Binocularity in comitant strabismus: II. Objective evaluation with visual evoked responses.

Campos (1982a) reported on his psychophysical studies on the binocularity of patients with comitant strabismus. With binocular visual field techniques, it was possible to show that patients with small-angle eso- and exotropia exhibit a binocular vision, without suppression of the deviated eye. In the present paper visual electrophysiology is used objectively these findings and to provide more insight in the problem. First, the studies on binocularity in normals and strabismics, done by using visual evoked responses (VER) are reviewed. This type of investigation is relatively new and the results of the literature are still conflicting. Then personal results of the authors are reported. It is shown that with VER it is possible to objectively assess the presence of anomalous binocular vision (ABV) sustained by anomalous retinal correspondence (ARC) in small-angle strabismus. In patients with large angle deviations this type of binocularity is absent. A correlation between psychophysical and electrophysiological data is provided. Lastly a simple method is described for differentiating the binocularity of normals from that of Strabismics with ARC. This method is based on the recording of binocular VER with the anteposition in front of the fixing eye of neutral filters of increasing density.

Adolescent↗

Plagiocephaly causing superior oblique deficiency and ocular torticollis. A new clinical entity.

Unilateral coronal suture stenosis provokes a shortening of the orbital roof of one side. It is argued that the effectiveness of the superior oblique muscle is reduced because of reduced length of its unreflected part and because of the increased angle between the reflected part of the tendon and ocular axis. This condition causes a clinical picture of superior oblique palsy, with ocular torticollis. We report four cases of this newly described clinical entity with various degrees of involvement of ocular motility.

Adolescent↗

Congenital nasolacrimal duct obstruction: therapeutic management.

PURPOSE: Congenital nasolacrimal duct obstruction is a common condition, and its diagnosis must be based more on regular in-time epiphora than mattering. The purpose of this study is to better define the diagnostic criteria and therapeutic strategy. METHODS: We have retrospectively evaluated 1563 subjects treated from 1990-1997 at the Pediatric Ophthalmological Service of Modena University Eye Clinic. The mean age at first examination was 5.7 months. According to symptoms and age, patients were treated with antibiotic therapy, office probing, or general anesthesia probing. Recovery was confirmed only after a 3-month symptom-free period. RESULTS: More than 29% of patients recovered spontaneously or with topical antibiotic therapy. Office probing reduced the number of patients who needed a general anesthesia probing (from 62.97% from 1990-1993 to 33.61% from 1994-1997). In the period from 1994-1997, we changed the technique and especially the age of patients, obtaining a clearing of the obstruction in about 86% of cases compared with a 39% rate in the earlier period. Since 1994, in cases of general anesthesia probing, we have used a midazolam and ketamine anesthesiologic technique that has reduced risks and increased parental satisfaction and cost-effectiveness. Also, our data show that age at first attempt highly influenced probing failure rate. CONCLUSION: If the first ophthalmologic examination is precocious and correctly timed, the possibility of curing the patient using the simplest method is increased. Better results can be obtained with cooperation among pediatricians, ophthalmologists, and anesthesiologists.

Anesthesia, Local↗

[Iridocyclitis and juvenile rheumatoid arthritis].

Iridocyclitis is a common complication of juvenile rheumatoid arthritis. It affects particularly female patients with mono-oligoarthritis. A positivity of ANA-test is usually observed, representing a marker for the disease. The course is chronic, leading potentially to scarring and blindness. The insidious onset, often not parallel to arthritis, requires careful ophthalmologic examination of all patients at risk, in order to achieve early diagnosis and treatment.

Arthritis, Juvenile↗