Biomedical subjects

C Cob

Publications and source records attributed to C Cob.

4 recordsLinked to original sources

PubMedDate not supplied

[Pleuropulmonary lesions due to Haemophilus influenzae].

Empyema due to Hemophilus influenzae has been reported only rarely. This report describes the cases of ten children with empyema due to this organism. Diagnosis was made through growth of the organism in pure culture from pleural effusion. H. influenzae empyema may occur in older children as well as in infants and, in contrast to certain other infections with this organism, empyema due to H. influenzae may be more common than is generally suspected.

Ampicillin↗

PubMedDate not supplied

[Finding of anaerobic bacteria in blood cultures].

Out of the blood cultures sent to the Bacteriology Laboratory of Hospital del Niño DIF, during the period of one year, in 1.4% of samples, isolation of anaerobic bacteria was obtained. Isolation was more frequent in infants under one year of age, but specially in newborns. The species most frequently found were Propionibacterium acnes, Bacteroides melaninogenicus and Clostridium subterminale. The presence of this finding in blood cultures of infants is noted, but there is no purpose to establish a clinical relationship with the finding of this group of bacteria.

Adolescent↗

PubMedDate not supplied

[Neonatal meningoventriculitis].

Clinical and autopsy data indicate that ventriculitis persists despite parenteral and intralumbar antibiotic therapy. In the present study, ventriculitis was documented as postmortem examination in nine newborns. These studies indicate that ventriculitis occurs commonly in neonates with meningitis, particularly when there is delayed sterilization of CSF culture, A clinician has to bear in mind the diagnosis of ventriculitis when: 1) There is poor clinical and/or laboratory response to the usual therapy. 2) He has a critically ill patient with lethargy, convulsions and bulging fontanels. 3) He culture an unusual organism. 4) He faces a suspected complication of meningitis: subdural effusion, ventriculitis or abscess. 5) A CSF from ventricular puncture with more than 150 WBC, glucose less than 50 mg. and protein more than 200 mg.

Anti-Bacterial Agents↗

PubMedDate not supplied

[Cryptococcosis of the central nervous system].

The steps for diagnosis and treatment and the clinical course followed in three patients with Cryptococcus meningitidis are discussed. One of them was treated with 5-flurocytosine alone. Two consecutive patients were treated with a combination of 5-flurocytosine and amphotericin B. The objectives of the study were: a) to achieve a therapeutic response better than that which might be obtained with either drug alone, b) to use lower doses of 5-fluorocytosine and amphotericin B in order to reduce toxicity, c) to extend treatment only for a period of four weeks, thus decreasing the period of hospitalization. None of the patients has relapsed. A shorter time of hospitalization and reduction in toxicity, suggests that combined therapy is a safe and effective alternative to other regimens.

Administration, Oral↗