PubMed Health⌕ Search

Biomedical subjects

C Colosimo

Publications and source records attributed to C Colosimo.

At least 109 records · Page 6Linked to original sources
PubMed1992

Botulinum toxin as a treatment for blepharospasm, spasmodic torticollis and hemifacial spasm.

Fifty-two patients affected by focal dystonia or hemifacial spasm were treated with repeated injections of botulinum toxin. A clinical improvement was observed in all patients with blepharospasm; clinical benefit had a mean duration of 10 weeks. Clinical results were less impressive, but also favorable in patients affected by spasmodic torticollis and by hemifacial spasm. In the latter, the incidence of drug-induced paresis was much higher than that observed in patients with blepharospasm, even though the doses of toxin injected were significantly lower.

Adult↗
PubMed1992

Alpha-interferon therapy in a case of probable progressive multifocal leukoencephalopathy.

Probable progressive multifocal leukoencephalopathy (PML) was diagnosed on the basis of clinical picture and magnetic resonance imaging in a 63-year-old man with a complete remission of a non-Hodgkin's lymphoma. After the introduction of intramuscular alpha-interferon therapy, his neurological state and MRI findings showed a clear improvement. Eighteen months after the onset of first symptoms the patient has significantly recovered from both aphasia and motor impairment, and shows only a mild attentional deficit.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed1990

A case of epidermal nevus syndrome with carotid malformation.

Epidermal Nevus Syndrome (ENS) is characterized by linear verrucous lesions of the skin and congenital anomalies including bone deformities, eye and central nervous system (CNS) malformations. We describe a case of ENS associated with an abnormality of the carotid artery which is considered a risk for stroke.

Adult↗
PubMed1988

Meningeal hematopoiesis causing exophthalmus and hemiparesis in myelofibrosis: effect of radiotherapy. A case report.

Meningeal myeloid metaplasia (MM) is very rarely observed in patients with myelofibrosis. We report the occurrence of meningeal MM causing exophthalmus and fever in a patient with myelofibrosis secondary to polycythemia vera. A computerized tomography (CT) scan showed multiple intracranial and intraorbital enhancing masses. A needle aspirate of retrobulbar space confirmed the diagnosis of extramedullary hematopoiesis. The patient subsequently developed a rapidly worsening tumor-like syndrome with hemiparesis, aphasia, and loss of sphinteric control. The administration of radiotherapy caused a complete and stable regression of clinical symptoms and a marked reduction of MM masses.

Adult↗
PubMed1988

Latency of the auditory brainstem response (ABR) and head size. Evidence of the relationship by means of radiographic data.

The role of head size to determine the inter-subject variability of the auditory brainstem response (ABR) was investigated in 32 normally hearing adults (19 females, 13 males, aged 18 to 52). The ABRs were evaluated in respect to the absolute latency of waves I, III and V and the interpeak latencies I-III, III-V and I-V. Plain films of the skull (3 views) were also taken of each subject and several measures were calculated in order to obtain an evaluation of the dimensions of both the most rostral parts of the skull and of the posterior fossa. The radiographic data as well as the ABR parameters showed significantly shorter values in females than in males. There was a strong positive correlation between the two variables when a linear regression procedure was applyed. The highest value of the correlation coefficient (r = 0.8) was found in the relationship between the wave V latency and the posterior fossa measures. High r values and similar factors in the regression equation were also found after considering the subjects separately according to sex. These results show that the ABR latencies linearly increase together with the skull size as it appears in the X-rays, regardless of the subject's sex. We can consequently deduce that the length of the neural pathway is the main factor of inter-sex variability of the response.

Adult↗
PubMed1987

Abnormal fetal cerebral blood flow velocity waveforms as a sign of an aneurysm of the vein of Galen.

A cerebral midline cystic lesion was detected by real-time ultrasound in utero in the absence of other congenital abnormalities. Pulsed Doppler ultrasound assessment of fetal circulation demonstrated normal peripheral and intracardiac hemodynamics associated with decreased cerebral vascular resistance. Furthermore, a markedly turbulent flow pattern was evidenced within the cerebral lesion. The presence of a cerebral arteriovenous malformation with an aneurysm of the vein of Galen was suggested and the provisional diagnosis was later confirmed by computed tomography and carotid angiography performed after birth.

Adult↗
PubMed1985

CT findings in eclampsia.

Cranial CT was performed in five patients with eclampsia: densitometric modifications were present in all cases. Only one patient, who later died, displayed multiple foci of cerebral haemorrhage; all others presented bilateral, symmetrical, nonenhancing hypodensities with mass effect interpreted as cerebral oedema. At CT performed 7-14 days after interruption of the pregnancy, these characteristic hypodense lesions were no longer present while neurological symptoms disappeared.

Adolescent↗
PubMed1984

Multiple spinal meningiomas in children.

A case of a girl with multiple spinal meningiomas, without evidence of neurofibromatosis, is described. The patient first underwent the complete removal of an intradural tumour at the lower lumbar level, at the age of eight year. A second intradural meningioma, located at the upper lumbar level, was surgically excised after a five year symptom-free period.

Adolescent↗
PubMed1984

Surgically treatable growth retardation due to non-neoplastic pituitary-hypothalamic dysfunction.

Out of 90 children, examined because of growth failure, 15 have been treated surgically. The diagnoses were intrasellar arachnoid diverticulum or empty sella (5 cases), enlarged chiasmatic cisterns (5 cases), chronic 'occult' hydrocephalus (5 cases). Surgery was followed by an immediate increase in growth rate in almost all the cases, even if the result was persistent only in some subjects. In percentage, better results were obtained in patients with enlarged chiasmatic cisterns and chronic occult hydrocephalus than in patients with arachnoid diverticulum or empty sella. The evaluation of prolactin serum levels was demonstrated to be useful both in preoperative diagnosis and postoperative control.

Adolescent↗
PubMed1983

Hyperplastic cholecystosis: study by ceruletide-assisted cholecystography.

Five hundred and two patients with good opacification of the gallbladder were studied by means of ceruletide-assisted cholecystography. A high percentage (15.7; 79 patients) was found to have hyperplastic cholecystoses. So far 26 of these patients have been operated upon because of gallstones or painful symptoms. The x-ray diagnosis was confirmed in all cases. Compared with routine cholecystography, the powerful contraction induced by ceruletide appears to lead to a more frequent recognition of hyperplastic cholecystoses.

Adolescent↗
PubMed1983

Spontaneous thrombosis of an aneurysm of the great vein of Galen.

A case of a thrombosed aneurysm of the vein of Galen in a 9-year-old boy is reported. Previously, only ten clotted aneurysms of the vein of Galen have been described. In our case, thrombosis occurred spontaneously after birth. Clinical presentation was characterized by signs of hydrocephalus, with an abrupt deterioration after several years of satisfactory clinical evolution. The patient was successfully treated with a ventriculoperitoneal shunt.

Brain↗
PubMedDate not supplied

Convergent strabismus fixus in high myopic patients.

Patients with high myopia may develop a myopathy which frequently results in a sort of convergent strabismus fixus. Echographic and CT scan findings give evidence that a myopathic paralysis of the lateral rectus is supported by a slow pressure on this muscle squeezed between the lateral orbital wall and the enlarged eyeball.

Adult↗