PubMed Health⌕ Search

Biomedical subjects

C Constantinou

Publications and source records attributed to C Constantinou.

22 records · Page 2Linked to original sources

Reduction of the "horns" observed on the beam profiles of a 6-MV linear accelerator.

The presence of large "horns" was found while plotting beam profiles during acceptance testing of a 6-MV linear accelerator. The in-phantom off-axis ratio (OAR), measured at 22 cm off the central axis along the diagonal of a 40 X 40 cm field at dmax was found to be 1.19, while beam uniformity was within specifications at 10-cm depth. A change in the gun injection voltage and the replacement of the magnet surrounding the magnetron with one of greater strength resulted in a reduction of the OAR to 1.085. The beam uniformity at depth was maintained within specifications. An alternative solution of adding a modifying filter in the primary beam was considered undesirable because of the 20%-25% reduction in dose rate caused by such filters. The relationship between the energy, the intensity distribution of the beam, and the magnitude of the horns is discussed, and the beam profiles, isodoses, and central axis depth doses before and after the changes are compared.

Humans↗

Development of radiographic chest phantoms.

Diagnostic imaging studies, particularly in chest radiography, require adequate phantoms. Two such phantoms have been made and used; one is a semianthropomorphic phantom and the other is a geometric phantom with embedded test objects. These phantoms, constructed of epoxy resin-based solid water, are described in detail and compared to a common commercial phantom.

Calibration↗

An electron density calibration phantom for CT-based treatment planning computers.

In order to correct for tissue heterogeneities on a voxel-by-voxel basis during CT-based treatment planning, the relationship between the correction factor (CF) and the CT number in Hounsfield units (HU) for the scanner in use must be established. Since the relationship between CF and electron density (rho e) of various materials is well documented, the rho e vs HU is required for direct computation of the correction factors by treatment planning computers. A CT phantom with 18 different tissue substitutes has been used to establish the rho e vs HU relationship. A description of the phantom and its contents is given and the calibration of the CT function of the planning computer is discussed.

Calibration↗