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Biomedical subjects

C Cordle

Publications and source records attributed to C Cordle.

5 recordsLinked to original sources
PubMed2000

Setting up a multidisciplinary clinic.

Chronic pelvic pain can be a perplexing and complex problem, frustrating to both clinicians and patients. The traditional medical and surgical model does not always relieve symptoms, and many patients suffer years of pain and undergo multiple surgical procedures without long-term benefit. The biopsychosocial model for chronic pelvic pain gives clinicians the opportunity to broaden the scope for management. A multidisciplinary team can offer simultaneous assessment and management of somatic, behavioural and psychosocial components of the pain. Key members of the team are identified and their roles explored. Practical aspects of operating a multidisciplinary clinic are discussed. A multidisciplinary approach comprises many elements. Further research is needed to identify which are the essential elements to secure optimum outcome for the individual patient.

Chronic Disease↗
PubMed1992

Psychological aspects of miscarriage: attitudes of the primary health care team.

A questionnaire surveying the attitudes of general practitioners, health visitors, community midwives and district nurses towards the psychological aspects of miscarriage was distributed to a random sample of 50 staff in each professional group. The response rate was 78%. A large majority of all staff surveyed (76%) agreed that miscarriage is frequently associated with significant psychological distress and 90% agreed that women should be routinely encouraged to explore and discuss their feelings following such an event. Overall, health visitors and community midwives were seen to be the most appropriate members of the primary health care team to offer such counselling. The gap between perceived need and provision of care for women who have had a miscarriage is highlighted, and ways of narrowing this are discussed.

Abortion, Spontaneous↗
PubMed1988

Surfactant-associated proteins in tracheal aspirates of infants with respiratory distress syndrome after surfactant therapy.

We have developed enzyme-linked immunoassays (ELISAs) that measure major proteins that are associated with pulmonary surfactant. Using these ELISAs, we tested sequential tracheal aspirates from infants severely ill with respiratory distress syndrome (RDS) who had been treated either with exogenous surfactant or with placebo within 8 h of birth. On average, we found low concentrations of surfactant proteins in tracheal aspirates on Day 1 of life, with increases evident by Day 3. The surfactant used in this study (TA surfactant) contains only the low molecular weight (6 kDa) surfactant proteins and not the 35 kDa surfactant protein. As we expected, those who were treated with TA surfactant more frequently had detectable concentrations of low molecular weight surfactant protein on the second day of life when compared with control infants. No differences were evident in the concentrations of surfactant proteins between the 2 groups by Day 3, nor were differences evident between the 2 groups evident for 35 kDa surfactant protein during the first 3 days of life. Increased low molecular weight surfactant proteins in tracheal aspirates 1 to 2 days after surfactant therapy may occur either because of persistence of exogenous surfactant proteins and/or enhanced surfactant protein production. Comparisons with measurements from other groups of patients with RDS confirm that absence of both surfactant proteins reflects alveolar surfactant deficiency.

Enzyme-Linked Immunosorbent Assay↗