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Biomedical subjects

C Cornec

Publications and source records attributed to C Cornec.

9 recordsLinked to original sources

Measurement of cardiac output by the thermodilution method during left thoracotomy in the lateral position in the dog.

The validity of cardiac output measurement by thermodilution in the lateral position during thoracotomy was assessed. Three balloon thermodilution Swan-Ganz catheters were placed in the pulmonary artery trunk and the right and left pulmonary arteries in 12 mongrel dogs, after left thoracotomy had been performed. Cardiac output was measured simultaneously from two of the three sites. The cardiac output measurements show no significant difference related to the location of the catheter extremities: the mean cardiac index was found to be 2.164 +/- 0.448 l/min/m2 from the pulmonary artery trunk, 2.127 +/- 0.404 l/min/m2 from the left branch and 2.116 +/- 0.421 l/min/m2 from the right branch. It is concluded that the measurement of cardiac output during left thoracotomy is valid, whether the thermistor is situated in the pulmonary artery trunk or in a main branch to either the dependent or non-dependent lung.

Animals↗

[Functional reinnervation of the larynx. Experimental study (author's transl)].

This study of reinnervation of the larynx results from the research for a functional method of treatment for laryngeal paralysis of peripheral origin. The physiological reality of reinnervation of a denervated muscle by a nerve other than that anatomically destined for it, or "neurotisation", is now an established fact. This experimental study in 12 dogs consisted of neurotisation of a posterior crico-thyroid muscle, denervated by section of the recurrent laryngeal nerve, by implantation of a graft of sub-hyoid muscle with a nerve pedicle. Only one positive result at six months was seen. 8 failures could be explained by the absence of ventilatory difficulty necessary for the sub-hyoid muscles to be brought into action, and the other 3 failures two months after the operation by muscular fibrosis of the graft before neurotisation could occur. Physiology and the experience of other teams justify the continuation of this study.

Animals↗

[Meningo-encephalitis due to Candida albicans (author's transl)].

Meningo-encephalitis due to Candida albicans is frequently iatrogenic in origin and the factors leading to its appearance should be known (immunity disorders and more particularly indiscriminate prescribing of antibiotics). Diagnosis is usually difficult and direct examination of the CSF and culture on special media are necessary in order to demonstrate the presence o yeasts. Recovery is possible with present-day therapy (two out of the three cases reported).

Adult↗