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Biomedical subjects

C Cotrutz

Publications and source records attributed to C Cotrutz.

At least 19 recordsLinked to original sources

[Phlebectasia of the internal jugular vein post injury (author's transl)].

The authors present the case of a 14 year-old girl having the cervical deformity developed on the background of influenza and sore throat and was caused by an apparently minor sports injury, with vertebrocervical lesion and rupture of the inner wall of the jugular vein. The painful onset symptomatology, initially attributed to exacerbation of the anginous process and cervical adenitis, evolved towards phonation, deglutition, nervous and final respiratory disturbances. The progressive evolution and gravity of the clinical picture imposed craniocervical surgery, with exclusion of the lateral intramastoid sinus and resection of the extensive ectatic cervicoprevertebral pouch. The authors discuss the mechanism of the vascular lesion, the clinical picture, evolution, diagnosis and therapy, which totaly differed from classical descriptions of phlebectasia of the jugular vein.

Adolescent

Ultrastructural differentiation of the glomerular mesangium from the human metanephros.

In section of metanephros tissue obtained from 32 human embryos and fetuses, 8 to 24 weeks old, the mesangial cells differentiate beginning with the 12th week. Some of the cells from the central mass of the metanephros blastema showed endocytosis phenomena characteristic for the adult mesangial cells. In the 13th week the three cellular types from the renal corpuscle individualize, and from the 14th to the 16th week they acquired the adult morphological aspect.

Cell Differentiation

[Ultrastructural aspects in the development of the human heart. II. The endocrine cells of the embryonic heart].

Electronmicroscopic studies performed on atrial and ventricular tissue fragments from 9 human embryos, 8 to 15 weeks old, showed that in certain myocardiocytes, especially in the atrial ones, from the 10 weeks old embryos, there appear granules of secretion, very similar in morphology with those from adults, which had been demonstrated to contain the atrial natriuretic factor. The precocious appearance of this peptide represents a functional adaptation by which the embryo attempts at counterbalancing the actions of renin and angiotensin from the maternal circulation.

Atrial Natriuretic Factor

[Ultrastructural aspects in the development of the human heart. I. The cytoskeleton and motility of human embryonic myocardiocytes].

Electron microscopic investigations performed on heart tissue fragments from 12 human embryos. 8 to 15 weeks of age, showed that at the age of 8 weeks the myocardiocytes are poorly differentiated cells: they contain microfilaments of actin and myosin inserted on the cytoplasmic aspect of plasmalemma, a smooth endoplasmic reticulin and mitochondria, accounting for the early contraction. Gap junctions appear among myocardiocytes, confirming the myogenic theory of heart contractions. Within 10 to 15 weeks, actin and myosin myofilaments organize in sarcomeres. Eberth disks appear and numerous mitoses are to be seen.

Cell Movement