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C Cranz

Publications and source records attributed to C Cranz.

28 records · Page 2Linked to original sources

[Relation between spermatozoids and reducing sugars (glucose and fructose) in human seminal fluid].

The prostatic fraction of seminal plasma contains components that are involved in the process of transforming fructose into glucose. If a positive correlation can be found between the slope of the decrease of fructose (estimated to be between 30 minutes and 5 hours) and the sperm count, with at the same time the maintenance of a relatively constant glucose level, then we have been able to demonstrate that glucose is more efficient than fructose to keep spermatozoa mobile. The enzyme process involved in transforming fructose into glucose may thus act to maintain definite glyspermia with a maximum value of 1.8 g/l. Aspermia in some circumstances then can be related to the absence or poor function of the transformation process and thus with the absence or decrease in prostatic secretion.

Fructose↗

[Epididymal hypertrophy after subepididymal hemicastration].

Following hemicastration, the epididymis on the non-operated side progressively hypertrophies and remains in this state for an unlimited length of time. This modification is due to an increase in androgens from the remaining testicle via lymphatics and/or lumen. This increase in weight seems to be due to an increase of testicular content by activation of in situ cells.

Animals↗

[Study of the vascularization of the epididymis].

The pampiniform system plays an important role in the thermoregulation and the concentration of hormones in the testicle. The study of the vascularization of the testicle and of the epididymis shows an independent vascularity in the case of the rabbit. The arteries of the head of the epididymis leave the spermatic artery before the establishment of the particular relationships which exist between the testicular artery and the pampiniform system. Temperature monitoring shows no difference between these two organs. It appears in this case that the thermo regulation is achieved essentially by the scrotum. It is not possible to say if any hormonal exchange takes place between the testicle and the epididymis.

Animals↗

[Effect of short-term cyclophosphamide administration on rabbit sperm].

Daily injection in the rabbit of 60 mg cyclophosphamide, during four days, product during 8 to 9 weeks one importance decrease of the number and the mobility of the ejaculated spermatozoa. This interval correspond with the spermatogenesis and epididymal transit period. Low doses injections product only one mobility decrease.

Animals↗

Fructose, proteins and coagulation in human seminal plasma.

Fructose is produced and secreted by the seminal vesicles and it is believed to form tight bonds with certain proteins that are also of vesicular origin. Under normal conditions of liquefaction, fructose is totally dialyzable; however, blocking liquefaction by exposing semen to acidic conditions renders this sugar non dialyzable. Fructose therefore appears to play a role in the coagulation of semen. The formation of fructose-protein complexes may resolve physiological problems concerning osmotic pressure in the seminal vesicles: if all the fructose were present in free state, the osmotic pressure would be very high and incompatible with cell survival

Dialysis↗

Semen parameters and capacitation.

A relationship exists between several semen parameters and the ability of spermatozoa to capacitate. The increase of oligoteratozoospermia, which could be related to testicular dysfunction, is correlated with the decrease of the percentage of spermatozoa able to "capacitate". The increase of loss of motility with time, which could be related to abnormalities of the seminal fluid, is also correlated with a decreased number of spermatozoa able to "capacitate".

Adult↗

Comparative study of semen in diabetic and healthy men.

This study examines the consequences of diabetes on male reproductive function. We have studied a group of 18 diabetics (15 type I, 3 type II) age 24 to 40 years (mean 34 +/- 5.3) with duration of diabetes from 2 to 30 years (mean 11.8 +/- 8.3). This group was compared to 20 semen donors. In diabetics higher sperm (p = 0.0063) and round cell (p = 0.031) concentrations/ml as well as a higher total spermatozoa count (p = 0.023) were observed. The percentage of abnormal sperms were also higher. None of the couples had consulted for sterility and they had a mean of 2 children. In this group of patients, diabetes was not a cause of subfertility. Specific spermiological alteration in diabetics might reflect a testicular damage secondary to their diabetes or disease.

Adult↗

Robertsonian heterozygosity and male sterility.

Meiotic and synaptonemal complex studies using electron microscopy were carried out on infertile man with a 13/14 translocation. Synaptonemal complex analysis showed a typical trivalent with incomplete pairing of the acrocentric elements. The sterilizing effect caused by the failure of synapsis is discussed. This pairing failure has a diagnostic value and a poor prognosis.

Adult↗