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Biomedical subjects

C Cutting

Publications and source records attributed to C Cutting.

21 records · Page 2Linked to original sources

Skin flap delay procedures: proximal delay versus distal delay.

An experimental study was designed to determine which portion of a flap, distal or proximal, contributes more to the delay phenomenon. (Since flap necrosis usually occurs in it distal portion, it is often assumed that only this portion of a flap must be delayed to improve flap survival.) Random-pattern pig flank flaps (16 X 3 cm) were used. All control flaps survived to at least 8 cm. Survival of flaps in which the distal half was delayed was not significantly different from that of controls. Survival of flaps in which the proximal half was delayed was significantly greater than undelayed controls. Completely delayed flaps, however, had significantly better survival than any other group. These findings are inconsistent with the metabolic adaptation hypothesis. They suggest that the denervation supersensitivity-arteriovenous anastomosis hypothesis is incorrect. They are consistent with the vascular collateral hypothesis and the new basal capillary shunting hypothesis.

Animals↗

An experimental neurovascular island skin flap for the study of the delay phenomenon.

We present an experimental neurovascular island skin flap. It is a consistent, reproducible model which produces a definite pattern of surviving skin flap area versus skin flap necrosis. There is a constant, anatomically definable nerve and vascular supply to the flap. This model permits independent experimental manipulation of the neural, arterial, and venous supply to the skin. It is useful, therefore, for the study of the vascular mechanisms of the skin microcirculation. We also demonstrated that increased flap survival can be produced by a delay involving denervation alone (leaving the vascular supply intact) or by devascularization alone (leaving the nerve supply intact). We conclude that both the adrenergic denervation and the ischemia contribute to the production of the delay phenomenon. We suggest that sustained vasodilation--vascular smooth muscle relaxation--is the vascular mechanism that accounts for the delay phenomenon.

Abdominal Muscles↗

Trapezius osteomyocutaneous island flap for reconstruction of the anterior floor of the mouth and the mandible.

The anterior mandible defect following cancer excision presents a formidable reconstructive challenge. A trapezius osteomyocutaneous island flap based on the transverse cervical vessels is described which allows immediate reconstruction of the entire defect. The various classes of bone flaps retaining an intact vascular pedicle are discussed. The osseous extension of the trapezius island flap appears to be adequate perfused. The anatomy involved and the orthopedic sequelae of using flap are discussed.

Arteries↗