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Biomedical subjects

C D Goldsmith

Publications and source records attributed to C D Goldsmith.

3 recordsLinked to original sources

Microbial conversion of ethylbenzene to 1-phenethanol and acetophenone by Nocardia tartaricans ATCC 31190.

A culture of Nocardia tartaricans ATCC 31190 was capable of catalyzing the conversion of ethylbenzene to 1-phenethanol and acetophenone while growing in a shake flask culture with hexadecane as the source of carbon and energy. This subterminal oxidative reaction with ethylbenzene appears not to have been previously reported for Nocardia species. When N. tartaricans was grown on glucose as its source of carbon and energy and ethylbenzene was added, no subsequent production of 1-phenethanol or acetophenone was observed. The mechanisms of 1-phenethanol and acetophenone production from ethylbenzene are thought to involve a subterminal oxidation of the alpha-carbon of the alkyl group to 1-phenethanol followed by biological oxidation of the latter to acetophenone.

Acetophenones

Lead levels in small mammals and selected invertebrates associated with highways of different traffic densities.

Lead levels in small mammals were studied in 6 areas -- 3 associated with highways of different traffic densities, and 3 control sites in forested areas. Lead levels were also studied in insects from 2 traffic areas and in earthworms from different distances from 2 traffic areas. Lead levels were low in insects ranging from 3.84 microng/g to 3.35 microng/g. Lead levels in earthworms were highest in those recovered closest to highways and from the area with the higher traffic volume. Lead levels in mammals generally was highest in mammals from areas of higher traffic densities. Higher levels of lead were found in shrews than in Peromyscus and Microtus.

Animals

Lead concentrations in soil and vegetation associated with highways of different traffic densities.

Soil lead levels were found to decrease significantly in all traffic areas as distance from the highway increased. Areas of higher traffic volume had greater soil lead levels. Strong trends were shown in vegetation with areas of greater traffic density having greater lead levels than areas of lower traffic density. A decrease in lead levels was also noted in vegetation as distance from highway increased.

Lead