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Biomedical subjects

C D Griffith

Publications and source records attributed to C D Griffith.

43 records · Page 3Linked to original sources
PubMed1983

Undernutrition in elective colorectal surgery. Implications for post operative morbidity.

The nutritional status of 65 patients undergoing elective colorectal surgery was assessed using 5 conventional nutritional indices, percentage ideal weight, mid arm muscle circumference, triceps skin fold thickness, serum albumin and serum total iron binding capacity. Only 9 patients had values for all five indices which are taken to represent normal nutritional status. This survey suggests that many patients undergoing elective colorectal surgery in this country have subnormal values of the indices commonly used for nutritional assessment but only severe depression of serum albumin however appears to adversely affect the outcome of surgery.

Journal Article↗
PubMed1982

Cholecystoduodenocolic fistula following abdominal trauma.

A case of cholecystoduodenocolic fistula following trauma is reported. It is unusual in that the majority of such fistulas are seen in relation to gallstones. The patient was managed initially by total parenteral nutrition and drainage followed by successful operation.

Abdominal Injuries↗
PubMedDate not supplied

Thromboembolic complications with silicone elastomer subclavian catheters.

Central venous thrombosis is a well-recognized complication of plastic catheters used during parenteral nutrition and occurs in up to 33% of cases if examined venographically. Silicone elastomer catheters, in addition to their favorable handling properties, are less thrombogenic than plastic varieties and are now increasingly used for parenteral nutrition. However, their use does not prevent the possibility of catheter-related thrombosis as this study demonstrates. In a consecutive series of 118 silicone elastomer subclavian catheters, 83% of which were used for parenteral nutrition, two instances of clinically apparent catheter-related thrombosis occurred and one of these was complicated by major pulmonary embolism. Catheter malplacement, catheter infection, and coagulation abnormalities were absent. Both catheters were used for parenteral nutrition and were in place for 20 and 28 days, respectively. Twenty-eight consecutive silastic catheters used for parenteral nutrition were studied, prior to removal, by simultaneous bilateral ascending phlebography. One clinically inapparent nonocclusive, catheter-related thrombus was detected which detached during catheter removal. This study suggests an incidence of symptomatic and asymptomatic silastic catheter-related thrombosis to be around 4%. Silicone catheters therefore may reduce but cannot abolish catheter-related thrombosis. Furthermore, when present, catheter-related thrombosis may be a source of major pulmonary thromboembolism.

Adult↗
PubMedDate not supplied

Delayed hypersensitivity skin testing in elective colorectal surgery and relationship to postoperative sepsis.

Delayed hypersensitivity skin testing to five common recall antigens (Varidase, Candida, PPD, Trichophyton, and Mumps) was performed on 50 patients undergoing elective colorectal surgery. Eighteen patients showed an altered response to skin testing (11 relative anergy, seven total anergy) and this group of patients had a significant increase in both total septic complications (p less than 0.001) and major septic complications (p less than 0.05) following operation. Anergy in these patients did not correlate with nutritional status, but it did relate to stage of the tumor in patients with cancer. The low specificity of abnormal delayed hypersensitivity skin testing and its failure to be related to malnutrition limits the practical application of this technique in patients undergoing elective colorectal surgery.

Adult↗