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Biomedical subjects

C D Gupta

Publications and source records attributed to C D Gupta.

At least 19 recordsLinked to original sources
PubMed1999

Complementary role of two fragments of domain V of 23 S ribosomal RNA in protein folding.

We have shown that the domain V of bacterial 23 S rRNA could fold denatured proteins to their active state. This segment of 23 S rRNA could further be split into two parts. One part containing mainly the central loop of domain V could bind denatured human carbonic anhydrase I stably. This association could be reversed by adding the other part of domain V. The released enzyme was directed in such a way by the central loop of domain V that it could now fold by itself to active form. This agrees with our earlier observation that proteins fold within the cell posttranslationally, a process that is completed after release of the newly synthesized polypeptide from the ribosome (Chattopadhyay, S., Pal, S., Chandra, S., Sarkar, D., and DasGupta, C. (1999) Biochim. Biophys. Acta 1429, 293-298).

Animals↗
PubMed1992

Reconstitution of denatured E. coli alkaline phosphatase with E. coli ribosome.

E. coli alkaline phosphatase was denatured by physical/chemical means. In vitro reconstitution of this denatured enzyme was assisted by 70S E. coli ribosome, as shown by the recovery of its catalytic competence. Almost total recovery of activity of the totally inactivated enzyme was obtained in presence of equimolar concentration of 70S ribosome at 50 degrees C.

Alkaline Phosphatase↗
PubMed1992

Epidemiology of rheumatic and congenital heart diseases in school children.

A stratified random sample of 10,263 school-going children in the age group of 6-16 years from government and private schools were screened for the prevalence of rheumatic fever, rheumatic heart diseases and congenital heart diseases. Fourteen children were found to have rheumatic heart disease with valvular lesions either single or in combination eg, pure mitral stenosis (6 cases), mitral regurgitation (4 cases), combined mitral stenosis and mitral regurgitation (3 cases) and aortic and mitral regurgitation (one case). Eight children had congenital heart diseases in the form of ventricular septal defect (3 cases), atrial septal defect (2 cases), patent ductus arteriosus (2 cases) and congenital bicuspid aortic valve (one case) while none had active rheumatic fever.

Adolescent↗
PubMed1988

A study of cranio-facial indices in Uttar Pradesh crania.

Various cranial and facial measurements were taken on 300 adult skulls available in the Department of Anatomy, S. N. Medical College, Agra and the cranio facial indices were calculated. When the measurements were statistically analysed, we have found a positive correlation between the basion prosthion length and the maximum cranial length, maximum cranial breadth and the bizygomatic breadth, nasion prosthion length and basion bregmatic height, and the palatal breadth and palatal length. The regression line between the various pairs of parameters were also calculated and a regression formula derived.

Cephalometry↗
PubMed1986

Arterial submucous plexus of duodenum (1st 2.5 cm): vascular etiology in duodenal ulcers.

The arterial submucous plexus in 5 human duodena (1st 2.5 cm of duodenum) were studied by injecting India-ink. The submucous plexus was richly vascular, which excluded the possibility of the end arteries to be the causative factor in production of ulcers in this region. Perhaps, the ulcers in this region may be due to obstruction of blood flow caused by traction of an over filled stomach.

Arteries↗
PubMed1984

Peroneal tubercle and its variations in the Indian calcanei.

A total number of 1,410 calcanei of either sex belonging to people of Agra and Lucknow region were studied and classified into 4 types depending upon the pattern of peroneal tubercle. A significant difference in the incidence of various types in the two regions were observed.

Adult↗
PubMed1984

Intrarenal arterial pattern of human kidney--corrosion cast study.

Study of intrarenal arterial pattern of kidney by corrosion cast method has been carried out on 100 kidneys obtained from post mortem bodies. The abnormal origin of renal artery is rare --only 3 percent. Renal artery divided extrarenally in 71 percent, intrarenally in 16 percent and at the hilum in 11 percent cases into anterior and posterior divisions. Renal artery did not divide into 2 divisions but continued as anterior division and divided into upper, middle and lower segmental arteries in one percent. The branching pattern of anterior division shows 5 different variations. Posterior segmental artery showed 3 different patterns. Variations in the origin of apical segmental artery were divided in 7 types and that of lower segmental artery in 5 types. The variations in origin of upper and middle segmental arteries were also observed. There were variations in the intrarenal branching pattern of all the segmental arteries.

Aorta, Abdominal↗
PubMed1984

A cephalometric study of 500 adult male medical students of Uttar Pradesh.

Various measurements of the head and face were made on 500 male medical students of the S.N. College, Agra (India) and the possible indices were calculated. The regression lines were calculated between the nasal index and the upper facial index as well as between nasal index and the total facial index. A significant correlation was found between the above three indices. A formula was derived, by which if one index is known the other can be calculated.

Adolescent↗
PubMed1982

Study of venous segments in the spleens of buffalo and dog.

By preparing the corrosion cast of the splenic vein and its intrasplenic tree, venous segments have been observed in the spleens of buffalo and dog. The buffalo spleen showed the presence of two venous segments (a dorsal and a ventral) in 85% of cases and three (a dorsal, an intermediate and a ventral) in 15% of cases. The spleen of the dog revealed only two venous segments (a dorsal and a ventral) in all the specimens. The results are compared with descriptions available in the literature.

Animals↗
PubMed1982

Surface projection of arterial segments in the human kidney.

Study of intrarenal arterial segments of human kidney by the corrosion cast method has been carried out on 100 kidneys obtained within 24 h of death. The five arterial segments which are normally described, namely, apical, upper, middle, lower and posterior, were reduced to four in 46% of the kidneys due to either absence of the apical segment or fusion of the upper and middle or middle and lower segments. The number of segments was very rarely (1%) reduced to three due to the absence of the posterior and apical segments. The apical segment was absent in 15%. The upper and middle segments were combined in 14% and the middle and lower segments in 17%. The surface projections of different segments were variable depending upon the intrarenal branching pattern of the segmental arteries.

Arteries↗
PubMed1982

Intrahepatic patterns of the biliary ducts in the chick liver (Gallus gallus domesticus).

In 40 chick livers intrahepatic ductal patterns have been studied after preparing the corrosion cast of the hepatic duct. Frequently hepatoenteric duct was formed by the union of left and right hepatic ducts (92.5%) and rarely by union of left dorsal, left ventral and right hepatic ducts (7.5%). The left lobe of the liver was drained by left dorsal, left ventral and left intermediate hepatic ducts and the right lobe by the right dorsal and right ventral hepatic ducts. The various patterns of their formation and their sites of drainage into the ductal system have been described in detail.

Animals↗
PubMed1982

Study of Os japonicum in Uttar Pradesh crania.

The incidence of Os japonicum has been studied in 500 Uttar Pradesh crania, and is found to be 4%. Typical bipartile zygomatic bone das present in 40 instances. In 6 bones only a horizontal groove was seen on the temporal surface. In one skull the zygomatic process of maxilla and the zygomatic process of the temporal bone were articulating directly on the temporal surface of the zygomatic bone. In another skull the maxilla and the temporal bone were articulating with each other along the lower border of the zygomatic bone, giving the appearance of a tripartile condition. The cause and significance of this trait is discussed in the light of available literature.

Adult↗
PubMed1982

Intrahepatic topography of portal vein in the chick (Gallus gallus domesticus).

50 corrosion casts of Chick portal vein were studied to observe the various intrahepatic patterns of portal vein. The liver was supplied by right and left portal veins. Each one entered the liver through separate hilus. The right lobe of the liver received its portal supply from 2 principal veins: a right dorsal and a right ventral. In addition to the above 2 principal veins 2 minor veins were also observed in majority of cases--one supplied the central region (68%) and other the ventral region (52%) of the right lobe. The left lobe of the liver received its portal blood through left dorsal, left ventral and left intermediate veins. The various sites of origin of the veins of the portal system have been described.

Animals↗