Biomedical subjects
Publications and source records attributed to C D Triantaphyllidis.
PAGIF was used to investigate the distribution of Gc and Tf subtypes in a Greek population sample. The gene frequencies were compared to those reported for other European populations.
Gene frequency data on 16 protein and blood group loci for the inhabitants of 9 Mediterranean countries were collected from the literature. The frequency of most of these genes was associated with longitude. The genetic distances between the same populations were also determined. The smallest genetic distances were found among the north Mediterranean countries, whereas the highest values were observed between the Algerians and the inhabitants of the other countries.
The placental alkaline phosphatase (Aph) polymorphism was studied in Northern Greece. A new rare placental Aph variant was described.
A study was carried out dealing with the acid phosphatases, in larvae, pupae and adults of Drosophila auraria. The most interesting finding is that the acid phosphatases are observed in 3 different phenotypes appearing as groups of 3 bands of different mobilities in the homozygotes and giving a 5 band phenotype in the heterozygote. A hypothesis is discussed in an attempt to explain the phenotypes observed and their variation during the development of the species.
The polymorphisms of the complement components C2, C3, C4 and BF have been studied in a sample of 166 unrelated individuals from Northern Greece. The C3*F and BF*F allele frequencies of Greeks are within the range of frequencies reported from Europe. A single individual with a rare heterozygote variant C2C/C2A was found in Greeks. This C2*A allele was found for the first time in European Caucasoids. For the C4 system six different alleles were found at both C4A and C4B loci. There were a low frequency of the null alleles at the C4A locus and a relatively high incidence of gene duplications in this system.