Progressive destruction of the elbow joints in a dog with leishmaniasis.
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Biomedical subjects
Publications and source records attributed to C D van Zuilen.
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Companion animals reach an older age because of advances in veterinary medicine. Pets with cancer are an important group of patients that are frequently presented to the general practitioner for diagnosis and treatment. In order to fulfill these demands it is essential to have basic knowledge about cancer and its treatment. The surgeon plays an important role in the treatment of companion animals with oncologic diseases. Surgery is one of the most successful treatment options for many tumor types. A radical surgery after an accurate diagnosis results in the best chance for a total cure. The goal of this article is to review the important principles of oncologic surgery. Topics such as biopsy techniques, and oncologic surgery techniques will be discussed.
Xanthine calculi were found in a 7-month-old male Cavalier King Charles spaniel with urethral obstruction and renal insufficiency. Because the only two other reported cases of naturally occurring xanthine urolithiasis concerned a Cavalier King Charles and a King Charles spaniel the urine of the littermates and parents of the patient were also examined for xanthinuria. Semi-quantitative analysis revealed high urine concentrations of hypoxanthine and xanthine in the patient and his female littermate. Quantitative analysis by high-pressure liquid chromatography (HPLC) of the urine samples from the family of this Cavalier King Charles spaniel and nine control dogs revealed that hypoxanthine and xanthine excretion was 30 and 60 times higher in the affected patient and the female littermate than in the others dogs. The pattern of xanthinuria, which is caused by a deficiency of the enzyme xanthine oxidase, in the relation diagram of this family of Cavalier King Charles Spaniels was consistent with an autosomal recessive mode of inheritance.
Surgical oncologic emergencies are relatively common and pose a clinical and therapeutic challenge for the emergency clinician. This article provides a clear clinical reference for assessment and management of some common surgical emergencies in cancer patients.
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