Biomedical subjects
C DE DUVE
Publications and source records attributed to C DE DUVE.
Distribution of enzymes between subcellular fractions in animal tissues.
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Effects of fat-soluble compounds on lysosomes in vitro.
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Intracellular localization of catalase and of some oxidases in rat liver.
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Tissue-fractionation studies. 14. The activation of latent dehydrogenases in mitochondria from rat liver.
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Tissue fractionation studies. 15. Intracellular distribution and properties of beta-N-acetylglucosaminidase and beta-galactosidase in rat liver.
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Tissue fractionation studies. 9. Enzymic release of bound hydrolases.
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Tissue fractionation studies. 10. Influence of ischaemia on the state of some bound enzymes in rat liver.
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Tissue fractionation studies. II. Influence of various hepatotoxic treatments on the state of some bound enzymes in rat liver.
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Tissue fractionation studies. 12. Intracellular distribution of some dehydrogenases, alkaline deoxyribonuclease and iron in rat-liver tissue.
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Tissue fractionation studies. 13. Analysis of mitochondrial fractions from rat liver by density-gradient centrifuging.
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[Various aspects of the physiopathology of the hepatic cell].
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[Lysosomes].
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The assay of glucagon on isolated liver slices.
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Carbohydrate metabolism.
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Intracellular localization of esterase in rat liver.
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Electron microscopy of lysosomerich fractions from rat liver.
A preliminary electron microscope study has revealed the presence in lysosome-rich fractions, isolated from rat liver, of hitherto undescribed cytoplasmic particles, called "dense bodies." Approximately 0.37 micro in length, the dense bodies often possess an internal cavity and external membrane. They contain many electron-dense granules 55 to 77 A, or less, in diameter. Such dense bodies are also visible in electron micrographs of parenchymatous cells in liver sections. The correlations between dense bodies and lysosomes are listed, but until pure preparations are available it is not possible to assert that dense bodies and lysosomes are identical.