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Biomedical subjects

C Danner

Publications and source records attributed to C Danner.

13 recordsLinked to original sources

[Anonymous birth and neonaticide in Tyrol].

BACKGROUND: In 2001 the Austrian government provided the legal means that formally enabled "anonymous birth": a woman can now give birth in any hospital in Austria without giving her name or insurance number, the baby is taken into care by social services and placed with adoptive parents. The cost of the hospital stay is covered from public funds. These measures were put into effect after some highly publicized cases of infant abandonment and neonaticide in Austria. METHODS: In the mostly rural and small-town province of Tyrol province in western Austria (687,000 inhabitants, 7000 births per year) four cases of neonaticide were discovered in the years from 1996 to 2004. One child was abandoned inside a hospital. Since 2001 two women have made use of the "anonymous birth" option. Neither had had any pregnancy controls, both showed up at or near term with contractions. They delivered healthy infants that were then taken into care by local adoption services. Both women were extensively counselled by psychologists, social workers, medical and midwifery staff and both insisted on their original decision to remain anonymous. A few weeks later one of the women found herself at the centre of a criminal investigation for infanticide after anonymous letters were sent to family members insinuating she had done away with the child. Police stopped that investigation when hospital staff confirmed that the woman had had an "anonymous" delivery. RESULTS: Despite the option of legal "anonymous" birth free of charge in modern hospitals there are still cases of infant abandonment and neonaticide in Austria. It is proposed that the women who opt for anonymous birth may not be the women who would otherwise kill their babies. Instead, it appears that the women opted for anonymity to escape the probably well-intentioned but overbearing attention of their families and of social services. It is doubtful that the option of anonymous birth will lead to a complete disappearance of infanticide and infant abandonment in Austria.

Adoption↗

Primary basal cell carcinoma of the middle ear presenting as recurrent cholesteatoma.

OBJECTIVE: This study aimed to sensitize the practitioner to the unusual presentation of basal cell carcinoma in a recurrent cholesteatoma mass. STUDY DESIGN: The study design was a case report format. SETTING: The study was conducted at a tertiary referral hospital. PATIENT: The patient studied was a contralaterally anacusic veteran. INTERVENTION: Interventions were excision of cholesteatoma and withholding of adjunctive radiation. CONCLUSION: Primary basal cell carcinoma may present in a revision cholesteatoma field.

Biopsy↗

Cognitively impaired elders. Using research findings to improve nursing care.

1. Cognitive changes may be similar in people with Alzheimer's disease, but each person loses abilities differently, and each individual responds differently to interventions. 2. Assessment of cognitive function is needed in order to design appropriate interventions that will be specific in facilitating independence in cognitively impaired elders. 3. Research findings suggest that functional ability in cognitively impaired elders can be maximized by assessing cognitive abilities and using this information to tailor specific interventions that will facilitate independence.

Aged↗

Cryptorchidism in adults.

Semicastration in cryptorchidism of adults is the preferential therapy. A positive effect on fertility is usually to be expected. An aggravation did not occur in any case. If for any reason, in cases of cryptorchidism or especially if only one testis is present orchidopexy is carried out, there should be a periodical check-up of the patients in order to discern in time the development of a testicular tumor.

Adolescent↗

Spermatogenesis in men treated with injections of medroxyprogesterone acetate combined with testosterone enanthate.

The effects of a combination of medroxyprogesterone acetate and testosterone enanthate, on the exocrine and endocrine testicular function were examined in adult men. The treatment was carried out with 2 different regimens and lasted for 8 months. Group I received an initial injection of 1000 mg medroxyprogesterone acetate and 500 mg testosterone enanthate followed by monthly maintenance dose of 150 mg medroxyprogesterone acetate and 500 mg testosterone enanthate. In group II, after an initial high dose of 1000 mg medroxyprogesterone acetate and 250 mg testosterone enanthate treatment was given as biweekly injections of 75 mg medroxyprogesterone acetate and 250 mg testosterone enanthate. Complete spermatogenic arrest of variable duration was achieved in all 9 subjects enrolled. Restoration of spermatogenesis occurred in both groups, in a few cases during the treatment, and there was a delay of full recovery of sperm counts up to 5 months after cessation of therapy. None of the subjects enrolled in this study complained of decrease in libido or change in sexual behaviour. Clinical evaluation and measurements of various urine and serum components revealed no significant changes during the treatment period. The dosage and the different administration schedule of the hormone combination described here was inadequate to maintain azoospermia in all subjects during treatment.

Adult↗

Testicular function after torsion.

A group of 20 patients with torsion was investigated. The study indicated that immediate surgical intervention with a period of torsion of the testis of less than 6 h will prevent impairment of testicle function. The histology of testicular biopsies taken from such patients revealed only interstitial oedema and, at the most, partial necrosis. If torsion time exceeded 6 h testicular histology revealed severe alterations, and surgical correction could not prevent atrophy of the testis. Patients with pathological spermiograms showed FSH values over or at the upper limit of the normal range. As far as can be concluded from one single basal hormone determination, the testosterone secretion remained unaltered. Libido, potency and virilization remained normal.

Adolescent↗

Androgen substitution with testosterone containing nasal drops.

Testosterone proprionate in form of eye drops will not be absorbed. A good absorption takes place following the administration of testosterone containing nasal drops in the form of an emulsion of pure testosterone. A quick, significant testosterone increase but of only short duration takes place. Unpleasant side effects were not observed. This treatment may be clinically applicable to male patients in the climacteric period.

Administration, Intranasal↗

The effect of chronic administration of a synthetic LH-RH analogue intranasally in cryptorchid boys.

Eighteen boys with either unilateral or bilateral cryptorchidism were treated with a synthetic LH-RH analogue ("D-Leu 6, Des-Gly-10 LH-RH ethylamide") intranasally. The peptide was dissolved in aqueous solution (25 micrograms in 0,2 ml) and administered in the form of nasal drops. The patients were divided in two groups: in group A, 50 micrograms of the synthetic LH-RH analogue were administered intranasally every 48 h for 36 days; in group B same dose was given every 24 h. Additionally, in 4 cases a LH-RH test prior the trial was performed with the same peptide. The nasal administration resulted in a fivefold increase of LH and of FSH plasma concentration in 30 min and in 60 min, respectively. The endocrine profiles for T, LH and FSH were studied in each group over the treatment period and in group B (same dose was given every 24 h) a significant decrease of the LH and FSH plasma levels could be found. The clinical effect of treatment was same in the both groups. In the whole material 44% had either unilateral or bilateral descent of the testis after the therapy.

Administration, Intranasal↗

Lingual thyroid: iodine 131: a viable treatment modality revisited.

PURPOSE: Lingual thyroid has a reported incidence between 1:10 and 1:100,000. When symptomatic, patients may present with dysphagia, choking, and/or dyspnea. Current surgical treatment options range from tumor extirpation or transposition to excision and reimplantation. Tracheotomies are often performed postoperatively for reliable airway control. Iodine 131 (131I) has not been a popular modality of treatment for lingual thyroid because of theoretical fears of increased airway obstruction from thyroiditis. We believe that these fears were not substantiated, and that symptomatic patients needed a reliable, nonsurgical treatment option. Therefore, our goal was to further investigate the use of 131I for the treatment of symptomatic lingual thyroid. PATIENTS AND METHODS: A 6-year retrospective chart review was performed. From 1994 to 2000, 2 patients with symptomatic lingual thyroid presented to the Arkansas Cancer Research Center Head and Neck Oncology clinic, University of Arkansas for Medical Sciences, Little Rock, AR. Patients underwent pretreatment computed tomography, and iodine 123 scans. They then received 1 oral dose of 131I. Doses ranged from 30 to 85 mCi. Patients were then followed daily for signs of airway compromise. RESULTS: Complete resolution of symptoms was seen 2 months after treatment. Patients did not complain of any increased airway compromise during treatment initiation. Patients remain symptom-free and are maintained on thyroid hormone replacement. CONCLUSIONS: Iodine 131 ablation of lingual thyroid is a safe and effective treatment in symptomatic patients and should be included in the algorithm when formulating a treatment plan.

Aged↗