The total artificial heart.
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Cardiomyopathies↗
Biomedical subjects
C DeLoach
Publications and source records attributed to C DeLoach.
Valproate metabolite concentrations in brain increase with chronic administration of sodium valproate.
Rats were treated chronically with sodium valproate for varying periods of time up to eight weeks. A statistically significant negative correlation between plasma concentrations of valproate-derived substances (VDS) and length of treatment was observed while a statistically significant positive correlation was found between brain VDS concentration and length of treatment. Liver VDS concentrations showed a tendency to decrease with time but this trend was not statistically significant. A new procedure was developed to measure the tissue levels of VDS.
Animals↗