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Biomedical subjects

C Deb

Publications and source records attributed to C Deb.

At least 37 records · Page 2Linked to original sources
PubMed1978

Effect of long-term treadmill running on gonadal activity in female rats.

Histochemical studies of delta5-3beta-HSD and G-6-PD activities in the ovaries of female rats undergoing long term-treadmill running showed a marked reduction. This change was associated with increased concentration of total cholesterol and total ascorbic acid in the same organ. All these results suggest ovarian hypoactivity.

3-Hydroxysteroid Dehydrogenases↗
PubMed1977

Pentose phosphate pathway and testicular steroidogenesis in rats following oxythiamine treatment.

Suppression of delta5-3beta-hydroxy steroid dehydrogenase (delta5-3beta-OHD) and glucose-6-phosphate dehydrogenase (G-6-P-D) activities along with concomitant stimulation of succinic dehydrogenase (SDH) activity were observed in the rat testicular tissues following treatment with oxythiamine HC1, an inhibitor of pentose phosphate pathway. The same treatment also resulted in an accumulation of cholesterol and ascorbic acid in the gland associated with a decrease in the weights of seminal vesicle and prostate. The results suggest a diminution in testicular steroid biogenesis following an alteration of pentose phosphate pathway.

3-Hydroxysteroid Dehydrogenases↗
PubMed1976

A method for the estimation of free and esterified cholesterol involving thin-layer chromatography.

A method for the estimation of both free and bound cholesterol in serum and plasma involving thin-layer chromatography has been developed. The serum or plasma is applied as a band directly on the plate. Extraction of lipid material from this band and the chromatographic separation of the above components are carried out on the same plate. The components are extracted from the adsorbent directly with acetic acid and measured colorimetrically using iron(III) chloride-sulphuric acid reagent.

Acetates↗
PubMed1976

Leucyl naphthylamidase activity in pigeon and toad testes under various experimental conditions.

The activity pattern and functional significance of leucyl naphthylamidase (LNase) in the pigeon testis under different hormonal and photoperiod conditions as well as in the testes of short- and long-term HCG-treated toads have been studied histochemically. In both the species, the enzyme activity was present in the maturing spermatids and those embedded in the Sertoli cell components, the mature spermatozoa released in the lumen being devoid of any LNase activity. In pigeon, the stimulation of spermatogenic process was associated with enhanced activity of the enzyme, whereas arrest of spermatogenesis showed little or no activity. In toad, short-term HCG treatment caused mild stimulation of spermiation resulting in sperm release from the Sertoli cells and this was accompanied by moderate decrease in LNase activity. The long-term HCG treatment produced an enhanced stimulation of spermiogenesis and spermiation processes resulting in almost total disappearance of LNase activity. The above observations suggest that the enzyme in the testes of both species is related to spermiogenesis and/or spermiation events of spermatogenesis.

Animals↗
PubMed1975

Effect of different doses of ascorbic acid on thyroid activity in rats at different levels of dietary protein intake.

Rats, which can synthesize vitamin C, react similarly to graded doses of ascorbic acid as guinea pigs. Low doses of ascorbic acid stimulate and high doses inhibit the thyroid activity of rats which are supplied with normal and high percentages of protein. The stimulatory effect of low doses of ascorbic acid on hyperactive thyroid of high protein fed animals is additive. Ascorbic acid has no significant effect on the thyroid of low protein fed animals (deficient diet supplied for 21 days). In the initial stages of protein deficiency (deficient diet supplied for 11 days) the effectiveness of vitamin C on thyroid of rats was still significant. Deiodinase enzyme activity of peripheral tissues is markedly reduced in animals supplied with 2% of protein for 21 days, but this effect is less intense in animals supplied with 2% of protein for 11 days.

Animals↗