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Biomedical subjects

C Denie

Publications and source records attributed to C Denie.

6 recordsLinked to original sources

Gamma globulin administration in relapsing Clostridium difficile-induced pseudomembranous colitis with a defective antibody response to toxin A.

A 53-year-old woman suffered six episodes of Clostridium difficile-pseudomembranous colitis. The serological follow-up demonstrated the absence of a rise in IgG and IgA to toxin A. Human pooled gamma globulin was administered during the fifth relapse and raised IgG levels to toxin A. Normal stools reappeared a week later. The role of the antibodies to toxin A and gamma globulin in C. difficile colitis are discussed.

Bacterial Toxins↗

[Thrombus of the right atrium simulating myxoma in primary antiphospholipid syndrome].

Various thrombo-embolic complications have been related to the antiphospholipid syndrome. The authors report the case of a patient with a primary antiphospholipid syndrome associated with a right auricular mass highly suggesting a myxoma by both echocardiography and nuclear magnetic resonance imaging. Meanwhile, the histological examination of the operative specimen showed a well organized and calcified thrombus. Intracardiac thrombus has been rarely reported as a complication of the antiphospholipid syndrome. The preoperative investigations can't differentiate such a thrombus with a myxoma and the diagnosis is usually made postoperatively.

Antiphospholipid Syndrome↗

[Circulatory hyperkinesis of cirrhosis: etiopathogenesis, clinical and therapeutic implications].

A mysterious complication of cirrhosis is the progressive development of a hyperdynamic circulatory state characterized by high cardiac output and low peripheral and splanchnic arterial resistance. This particular hemodynamic state plays a major role in the progress of portal hypertension and sodium renal retention observed in cirrhosis. In this review, we try to better define the clinical impact and the etiopathogenic mechanism of the hyperdynamic state of cirrhosis.

Glucagon↗

Spontaneous exoneration of a colonic lipoma.

Colonic lipoma is a rare tumor. This tumor is usually asymptomatic. We report the case of a patient who complained of abdominal pain. Symptoms disappeared after spontaneous exoneration of a colonic lipoma.

Colonic Neoplasms↗