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C Di Benedetta

Publications and source records attributed to C Di Benedetta.

33 records · Page 2Linked to original sources

Glycosaminoglycans and glycoproteins in metachromatic leucodystrophy.

A study is reported of the brain glycoproteins and the glycosaminoglycans in a case of infantile metachromatic leucodystrophy, associated with a ponto-cerebellar systemic atrophy, verified by autopsy. The glycosaminoglycan concentrations in the grey matter were within the normal range, while in the white matter they were slightly increased. The glycopeptides from the soluble and insoluble glycoproteins of white matter were altered not only in their quantity but also in their composition. In the grey matter a decrease of all sugars except the NaNa was detected in the insoluble fraction while in the soluble no change was detected, except for a threefold increase of fucose. The relationship was discussed of soluble to insoluble glycoproteins, and a mechanism for their derangement in MLD was suggested.

Adult↗

[Individual characteristics and biological rhythms. VI. Circadian variations of body temperature].

It has been reported that body temperature fluctuates differently in evening and morning type subjects. In order to assess this finding in 779 university students the body temperature has been measured between 1986 and 1989. Body temperature exhibits circadian rhythm in 78.6% of subjects, but no differences between morning and evening type crest phases were found. Since this result contradicts literature data, the finding is discussed also on the basis of the difference of the percentage between our grouping and that of the other authors. Further studies are in progress in order to detect if the subjects of the two groups differ for other biological and psychological parameters as well.

Adult↗

Relation between the aortic pressure and the cardiac cycle in different neurovegetative conditions in the conscious dog.

The relation between mean aortic pressure (mAoP) and the duration of cardiac cycle (C) has been studied in resting conscious dogs in normal condition (n), after vagal blockade (vb), after sympathetic blockade (sb), and after combined blockade of the two systems (sb+vb). The relation has been found to be negative in all conditions. The different conditions are clearly differentiated by the slope of the relation between mAoP/C (= kPa/s = mW/ml) and C. The hypothesis is put forward that the balance between sympathetic and parasympathetic activities on the heart and the vessels produces the best compromise between the pump function of the heart and the afterload, in relation to the actual behavioural situation, in conscious animals.

Animals↗