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C Di Stefano

Publications and source records attributed to C Di Stefano.

29 records · Page 2Linked to original sources
PubMed1997

[Major renal trauma. Therapeutic approaches and our experience].

METHODS: During a 12-year period, 110 patients with renal blunt trauma have been observed. Renal exploration was performed in 17 patients (15.45%). Absolute indications for exploration were bleeding and pulsatile perirenal hematoma and associated abdominal injuries. Salvage was successful in 76.48% of the kidneys explored and hemostatic nephrectomy was required in 23.52%. The success rate was based on early vascular control and reconstructive techniques of renorrhaphy, partial nephrectomy and coverage with omental pedicle flaps. RESULTS: At follow-up, hypertension occurred in only 3 patients and resolved spontaneously after 3-6 months. CONCLUSIONS: On the basis of personal experience, the conclusion is drawn in that when renal exploration is required, reconstruction can be successful in a high percentage of patients.

Adolescent↗
PubMed1996

[The use of PGE1 in the treatment of erectile deficiency].

A total of 118 patients entered into a pharmacological erection program using prostaglandin E1 (PGE1) from September 1994 to November 1995. Of the men 20 (16.9%) used PGE1 on a regular basis, median duration of drug use was 4 months with a range of 2 to 14 months, while 66 (55.9%) failed to continue in the program after the dose titration period, (median duration of drug use 6 weeks), 32 (27.1%) failed to initiate PGE1 pharmacological erection program. There have been no instances of cavernous fibrosis, systemic reaction, penile pain after injection or priapism (erection present longer than 4 hours) in any patient; 24 (20.3%) men were unable to achieve an adequate erection with PGE1 intracavernous injections. PGE1 appears to have a lower risk of prolonged erections than other intracavernous agents and will continue to increase in popularity. However we report an interesting number of men who fail to continue (55.9%) or fail to initiate (16.9%) PGE1 therapy.

Alprostadil↗
PubMed1995

[Percutaneous nephrolithotripsy (PCNL). The authors' own experience with 106 patients].

The authors report 106 consecutive patients who underwent percutaneous removal or debulking of renal stones from March '88 to June '94. Removal was successful in 64 pts (60%), while 6 patients (5.6%) needed a second-look section and in one case (0.9%) a third-look; in 33 cases (31.3%) PCNL was performed as debulking procedure before ESWL. The major complications were: 1 severe haemorrhage with secondary nephrectomy, 2 respiratory complications, 1 intestinal fistula, 2 hyponatremic syndromes, 1 global kidney functional exclusion and 1 sectorial exclusion. PCNL is an effective technique to treat the majority of single big renal stone or debulking procedure in staghorn calculi before ESWL.

Female↗
PubMed1995

[Clinical effects of verapamil in the treatment of Peyronie's disease].

Calcium antagonist increase extracellular matrix collagenase activity as well as decrease collagen, fibronectin synthesis and secretion, altering fibroblastic metabolism. Preliminary findings reports that Verapamil improves would healing; Levine (1994) suggest that intralesional calcium antagonist (Verapamil) therapy offers an economical and sensible non operative approach for the treatment of Peyronie's disease. We studied and verified the effect of Verapamil in Peyronie's plaque on 39 men. They received injections of Verapamil bi-weekly in to the plaques for 6 months. Subjectively, improvement in rigidity was observed in 23,1% and a plaque softening observed in 48,7%. Rapid resolution of pain was verified in 90,9%. Objectively, curvature improved in 50% of those in which the diagnosis of Peyronie's disease was less than one year old, but in only 10.2% when disease lasted more than one year. A decreased plaque volume was not observed. There was no toxicity related to Verapamil effect. In this nonrandomized study we retained that Verapamil appears to result in an improvement in patients with symptoms lasting less than one year. For patients without pain with symptoms related to more than one year, Verapamil had no important effect.

Calcium Channel Blockers↗
PubMed1983

Correlation between increased serum and tissue L-carnitine levels and improved muscle symptoms in hemodialyzed patients.

A group of 14 uremic patients on intermittent hemodialysis was admitted to a cross-over double-blind trial in order to evaluate serum and muscle carnitine levels before and after 60 days of L-carnitine oral (2 g/day) treatment. The morphology of muscle fragments was studied by light and electron microscopy. Symptoms (asthenia, cramps) occurring during hemodialysis were also recorded. After L-carnitine treatment the blood and muscle levels of the metabolite increased simultaneously to reduced asthenia and cramps. Morphological examination of the muscle of 13 of 14 patients did not reveal any pre- or posttreatment pathological alterations. The presence of nemaline rods was morphologically diagnosed in only one case and was no longer observed at the second biopsy at 2 months of L-carnitine treatment.

Adult↗
PubMed1983

Plasma and muscle carnitine levels in haemodialysis patients with morphological-ultrastructural examination of muscle samples.

The present study investigates 14 patients on intermittent haemodialysis. Pre-dialysis blood and muscle samples taken for determining plasma free- and acetylcarnitine levels. The tissue fragments were used for light and electron microscopy studies. Our results support the findings of other investigators that patients on haemodialysis generally display decreased free- and acetylcarnitine levels both in plasma and skeletal muscle when compared with control values. Muscle carnitine deficiency was apparently more severe in the longer-term haemodialysis patients. Moreover, a significant correlation (p less than 0.05) between plasma and muscle free-carnitine values was found. Morphologically no pathological alterations were observed in the muscle fibres in 13 of the patients. Light and electron microscopic studies of the muscle fibre of the 14th patient showed a typical nemaline myopathy with rod bodies in the cytoplasm. The muscle free-carnitine concentration in this patient was among the lowest of the group.

Adult↗
PubMedDate not supplied

[Perception of alcoholism risk in health workers: medical role in prevention and surveillance].

According to Italian laws (legge 125/01, art. 15, comma 1) about safety on workplaces, it's forbidden alcohol drinking and taking for health workers (art. 8, comma 6, legge 5/06/2003 number 131) (e.g. anaesthesiology, surgery, radiology, nursing etc.). National alcoholism risk prevention program to assess number for year of accidents in health workplaces, is actually in progress leaded by Health Minister and Regional administration (e.g. Tuscany). Particularly, prevention program acts consist in comprehensive informations for health workers and their co- workers, about prevention and identification of alcoholism- related risks. To assess the size of alcohol problems in health workplaces, Occupational Health Medicine Institute of Second University of Naples is going to enrol 500 subjects (200 nursing students, 200 Specialist Registrars of different areas, 100 Consultants). Actually our population consists in 160 Specialist Registrars of different medical subjects (surgery, clinical and laboratory). To verify the importance of alcoholism risk perception, a not validated questionnaire was administrated. This original assessing instrument consists in 23 items with closed answers about demographic information, university, career, lifestyle, knowledge about rules taking alcoholic drinks. Results show a dangerous lack of information about alcohol health effects, even in Medical Specialist Registrars.

Alcoholism↗