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Biomedical subjects

C Diebler

Publications and source records attributed to C Diebler.

30 records · Page 2Linked to original sources

[Ischemic cerebral softening in newborn infants. Possible etiology of neonatal convulsive states].

The authors report on 8 cases of full term neonates presenting, between the 8th and 72nd hours of life, with several often subintrant partial seizures, always in the same area for a given child. Pregnancy, delivery and the first hours of life had been normal. The first CT scan (performed a few hours to 3 days after the first fits) showed a triangular hypodensity with internal vertex, still observed at the second examination, with reduced dimensions and fuzziness of the edges. The features and localization, always in an elective arterial area, suggested an arterial infarction. The date of occurrence, the probably embolic nature and the etiology of such an arterial ischemia are discussed. The clinical, electric and CT-scan homogeneity of the picture is emphasized, as it makes diagnosis easy. Prognosis is relatively favorable among neonatal seizures states, except for possible intellectual and epileptic sequellae.

Anticonvulsants↗

Aneurysms of the vein of Galen in infants aged 2 to 15 months. Diagnosis and natural evolution.

This is a report of seven cases of aneurysm of the vein of Galen (AVG) with a review of the clinical and radiological aspects of 48 cases in the literature. The natural evolution and pathophysiology of this vascular malformation are discussed. The clinical signs of this condition are often misleading. The appearance of AVG on CT is pathognomic. Surveillance of the vascular malformation and associated cerebral lesions can be maintained with subsequent CT. Spontaneous thrombosis of the aneurysm was observed in three cases. The diagnosis of thrombosis of the AVG was always made at operation or by histological examination. The radiological appearance of a thrombosed aneurysm is typical.

Cerebral Angiography↗

[Cerebral tomodensitometry (scanner) and accident sequelae: its medico-legal value].

The authors report their experience of one years use of a cerebral scanner in the investigation of the sequelae of head injuries, and the medico-legal interest of this discovery. It permits one to visualise the pathological processes responsible for the symptoms following head injuries and its is thus of major intetrest in legal medicine where the subjective factor in these symptoms is difficult to assess. Increasing considerably the proportion of definite etiologies in this pathology, the authors believe that this new method will become standard in the medico-legal assessment of head injuries.

Adolescent↗

[Torsion dystonia of the left upper limb probably due to a head injury. Calcification of the head of the right caudate nucleus discovered by tomodensitometric examination].

A young man (30 years) suffered a head injury in the course of a road accident. Four years after the accident, there was progressive development of hypertonia of the muscles of the left shoulder in association with certain movements, with torsion dystonia of the left upper limb. The presence of minimal neurological signs differentiated this cases from so-called idiopathic torsion dystonia. Tomodensitometry revealed an opacity of the head of the right caudate nucleus which was invisible on standard skull films. The authors discuss the physiopathology problems raised by this special case.

Adult↗

Value of magnetic resonance imaging in West syndrome of unknown etiology.

Magnetic resonance imaging (MRI) studies of 46 patients with West syndrome (WS) of unknown etiology were reviewed retrospectively. The criteria for cryptogenic WS were met by 25 and 21 were considered symptomatic because other types of seizure or psychomotor retardation were apparent before spasm onset. Computed tomographic (CT) scans were normal in 38 patients and showed diffuse atrophy in eight symptomatic patients. In five patients, MRI was more informative than CT, demonstrating one case of delayed myelination and four cases of focal lesion. The focal lesion in 2 of these patients was similar on MRI consisting of poor gray-white matter demarcation in the parieto-occipitotemporal region. Surgical resection was performed in one because of intractable seizures, and neuropathological examination revealed cortical dysplasia. The remaining two cases with focal lesion had increased signal intensity on T2-weighted images in the posterior frontal cortex and in the temporal lobe, respectively. Our data indicate that MRI is useful in some cases of WS, especially in demonstrating focal corticosubcortical lesions not visible on CT scan.

Brain↗

[Cerebral cysticercosis. Apropos of a case treated with praziquantel].

The authors report a case of cerebral cysticercosis in a 17 year-old adolescent. Partial seizures and moderate functional signs of intracranial hypertension were the presenting symptoms. Treatment with Praziquantel under corticosteroid therapy was successful with almost complete disappearance of radiologic abnormalities on the computerised tomographic examination performed 7 months after the end of treatment.

Adolescent↗