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Biomedical subjects

C Dimitriu

Publications and source records attributed to C Dimitriu.

28 records · Page 2Linked to original sources

[Treatment of duodenal ulcer with chemical sclerosis of the gastric mucosa. Preliminary results].

On the basis of experimental studies and of the results obtained, the authors have applied over the last two years, sclerosis of the gastric mucosa with fresh, sterile solution of hypertonic (66%) glucose in 25 patients with duodenal ulcers and cellular and vagal hyperacidity resistant to medical therapy. Mucosclerosis was associated with gastric drainage in 14 patients with duodenal ulcer complicated by stenosis or hemmorhage. Sclerosis of the gastric mucosa is a physiological intervention because it achieves the sclero-atrophy of the acid-secreting glands and vago-sympatic denervation in the gastric territory, while the storage function of the stomach is maintained. It was not followed by extra-gastric disturbances or antro-pyloric distonia. It is easy to perform from the technical viewpoint and has a high degree of fiability, providing constantly satisfactory clinical, functional and metabolic results. Chemical values of basal secretion have decreased in a constant manner but in 9 patients the values of induced acidity showed inconstant decreases. Gastro-antro-pyloro-duodenal transit was good and all operated patients have gained weight. No diarrhea, dumping or peptic recidives were noted.

Adult↗

[Complications of Crohn's disease (Clinical and anatomopathological observations on 13 cases)].

Malignization of Crohn disease remains the most severe complication, both due to its intrinsic gravity and to the major complications that it may induce such as: peritonitis--following suppurations and perforation of the involved intestinal segment; intestinal sub-occlusion or mechano-inflammatory occlusion, either tumoral or chronic leading to stenosis of the intestine; hemorrhage. Malignization of Crohn disease was found in 53,84% of the cases (7 out of a total of 13 cases, between 1968 and 1974). This allows to conclude that Crohn disease can be considered as a pre-cancerous disease.

Adolescent↗

Examination of human and animal leukemic cells by high contrast scanning electron microscopy.

Investigation of human or animal (sheep and ox) leukemic cells by scanning electron microscopy enabled the identification and study of some ultrastructural details of the cell surface. A more detailed visualization by the high contrast technique of the same cell surface was obtained, in this work, for the first time in the biological field. This technique allows a better interpretation of any zone of the preparation examined, irrespective of the species from which the cells are collected.

Animals↗

[Treatment of duodenal stress ulcer by means of chemical sclerosis of the gastric mucosa induced with a 60 percent glucose solution (results after 1--5 years)].

Sclerosing of the gastric mucosa with a 60% fresh sterile solution of glucose was applied in 60 selected patients with chronic conflictual duodenal ulcers, hyperacidic gastritis by vagal neurogenic hyper-reactivity, associated with ischaemic gastropathy developed on an sympathico-adrenergic background. The immediate operatory results were good. The late results (between 1 and 5 years) were as follows: the clinical, radiological and metabolic results were good in 57 patients. Gastric chemical analysis, the values of the hourly basal output remained high in 16,6% of the patients, and those of acidity stimulated by histamine administration remained high in 13,3% of the patients. No peptic recidive was recorded. Unsatisfactory late results were noted in 3 patients (of which forced indication of the method in one patient and non-association of drainage in two patients).

Adult↗

[Sphincterotomy in the surgical treatment of abscesses of the anorectal region].

In 29 patients with abscesses of the anorectal region the wall of the purulent collection was sectioned not only toward the tegumental surface but also to the anal canal with partial sectioning of the sphincter in 9 of the cases with superficial abscesses, and complete sectioning of the sphincter in the remaining 20 patients that presented with ischio-rectal abscesses, and with deep posterior anal abscesses. No relapse was noted and in none of the cases did anal fistulae or anal incontinence develop. In contrast with the scars that develop following surgery for fistulae, the scars that develop after sectioning of the sphincter for anorectal abscesses are supple and do not lead to deformation of the sphincter.

Abscess↗

[A case of abdominal pregnancy--a case report].

Rare anatomical variety, the ectopic abdominal gestation involve a high maternal and foetal risk. On report an abdominal gestation in the 2nd quarter of evolution at a 42 yrs. age of a female with multiple uterine leiomyomas, the diagnosis being establish by ultrasonography. The attitude in the same cases is decided by the foetal viability: if the foetus is in a life, the pregnant women is hospitalised and followed each day; if the foetus is dead, there are indication of surgery, the major problem being represented by the total or partial removed of the placenta.

Adult↗

[A comparative study of the laparoscopic and classic treatments of inguinal hernias].

AIM: of this study is to compare two similar groups presenting inguinal herniae, one group having laparoscopic herniography and the other having a Bassini or Fruchaud repair. METHOD: Since September 1994, in our department, patients presenting with symptoms of unilateral or bilateral inguinal herniae to our practice were offered the transperitoneal or preperitoneal approach as an alternative of open surgical repair. We considered the first 50 patients operated by laparoscopic technic (35 M and 15 F), age between 22-72 years (group A), and similar group operated by Bassini or Fruchaud technic (group B). All the patients had general anesthesia and perioperative antibiotics. In the group A we used Prolene, Mercilene or Plastex mesh. The following parameters were assessed: 1) operative time from incision to closure: 2) amount and type of analgesia required postoperatively; 3) morbidity related to the procedure; 4) interval before returning to full activity; 5) early recurrence rate; 6) hospital cost. RESULTS: The mean operative time for unilateral herniae in group A was 70 +/- 10 minutes versus 40 +/- 12 minutes in group B. Group A required to return to work was significantly shorter for the patients in group A (7 +/- 3 days) compared with group B patients (25 +/- 10 days). Although no recurrent herniae have yet been found in patients from either group; follow-up was only 2-18 months in the two groups. The cost of hospital care of group A patients exceeded that of group B by approximately 1.7 more. IN CONCLUSION: was consider that although is more expensive, the laparoscopic procedure in treatment of inguinal herniae, has more benefits for the patients.

Adult↗

[Left lumbar sympathectomy via the retro-pneumoscopic approach. The technical considerations].

Retropneumoscopic lumbar sympathectomy is performed with an increasing frequency as a treatment of chronic obstructive arteriopathies; though the method has limited indications. We present the operative technique as it was performed în the Colţea Surgical Department in 2 patients. We highlights on difficulties advantages and disadvantages of the method.

Arterial Occlusive Diseases↗

[The place of laparoscopy in assessing and treating a pain syndrome of the right iliac fossa].

The study is considering a trial of 87 patients (61 women 17 and 76 years old) admitted in our clinic between 1995-1996. The preoperative diagnosis was coincident with the laparoscopic one in 10 cases the laparoscopic one in 10 cases the laparoscopy completed the diagnosis and in 12 cases it showed out other organ's disease, evicting useless operations. In the 87 patients we performed: 53 appendectomies, 20 oophorectomies, 15 partial oophorectomies, 9 right adnexectomies, 2 adhesiolysis, 2 lymph node biopsies, 1 epiploic fringe excision for necrosis, 1 appendicular stump removal. The evolution was favourable in all patients, the mean postoperative hospitalization was 48 hours.

Abdominal Pain↗