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C Dimopoulos

Publications and source records attributed to C Dimopoulos.

At least 55 records · Page 3Linked to original sources

[Estimation of serum beta 2 microglobulin in carcinoma of the bladder (author's transl)].

beta 2 Microglobulin is a low molecular weight protein synthesised by lymphocytes and neoplastic cells. The authors measured levels of this substance in the plasma of 40 patients with carcinoma of the bladder and normal renal function. 26 subjects were used as controls. Plasma levels were markedly higher in the bladder carcinoma sufferers than in the normal controls. Levels were also higher in invasive carcinomas than in superficial lesions. beta 2 microglobulin may therefore not be considered to be a specific indicator of carcinoma of the bladder but rather as a factor offering the possibility of measurement of the secretory activity of tumour cells.

Adult

Selective testicular venography for the localization of undescended testicles.

Percutaneous venography of the internal spermatic vein was performed for the localization of unpalpable testicles in 5 patients varying from 4 to 45 years of age. The catheterization of the vein on the left side was successful in all 5 cases; and the testicle was localized and verified by surgery in all but one case in which a competent valve prevented the retrograde filling of the whole length of the vein down to the testicle. In the two patients with bilateral undescended testicles the right internal vein could not be identified in one patient, and in the other patient a semiselective injection was done into that vein which appeared to represent the spermatic vein, but the examination was not conclusive.

Adult

[Disseminated intravascular coagulation syndrome (D.I.C.) and carcinoma of the prostate (author's transl)].

Carcinoma of the prostate, above all when accompanied by bone metastases, may be associated with a disseminated intravascular coagulation syndrome. The problem was to determine whether even in the absence of metastases the coagulation state of prostatic carcinoma patients predisposes them to disseminated intravascular coagulation. The authors compared coagulation equilibrium in 13 patients with a prostatic adenoma and 21 with carcinoma of the prostate free of metastases or infection. Fibrin breakdown product levels were abnormally high in 85.7 % of the carcinoma patients (as against 46.2 % of the adenoma sufferers). Clotting factor XIII was decreased in 70 % of carcinoma patients (as against 48.5 % of those with an adenoma). One prostatic carcinoma patient in four shows evidence of latent intravascular coagulation even in the absence of bone metastases. This prevalence justifies thorough coagulation studies in all patients with carcinoma of the prostate.

Adenoma

Intravesical formalin for the control of intractable bladder haemorrhage secondary to radiation cystitis or bladder cancer.

During the last two years, 17 patients with haemorrhage due to radiation cystitis or bladder cancer have been treated by intravesical infusion of 10% Formalin solution. The results were very good in 9 cases, satisfactory in 3, while the remaining 5 cases were disappointing. The control of bleeding by Formalin was safe especially in patients with secondary haemorrhage due to radiation cystitis with no tumour recurrence.

Aged

A comparative study between direct testicular and pedal lymphography in dogs. (A preliminary report).

In 20 dogs, 12 bilateral and 8 unilateral pedal and direct testicular lymphographies were performed. Comparison between the two methods showed that pedal lymphography failed to visualize some of the regional lymph nodes of the testicle. Histological examinations of the excised testicles two months after the injection of the contrast material failed to show any significant abnormalities. The potential applications of direct testicular lymphography are discussed.

Animals

Diagnostic and therapeutic problems in Cushing's syndrome. Series of 7 cases.

A series of 7 patients (all females) with Cushing's syndrome are presented. The syndrome was due to an adenoma of the cortex in 4 cases, to a carcinoma in 1 and to bilateral adrenal hyperplasia in another. In the 7th patient the cortical hyperplasia was due to a bronchogenic carcinoma (ectopic production of ACTH). Surgery was performed in all patients except 1. In 5 patients (adenoma, carcinoma) the diseased adrenal was removed. In 1 patient a left total and a right subtotal adrenalectomy were performed. Out of those 7 patients 4 survived and 3 died. 1 died a few hours after surgery, another 3 months after operation and the last one was never operated on.

Adenoma

Transcatheter arterial embolization in the management of tumours of the urinary tract.

The technique of transcatheter arterial embolization in the management of malignant tumours of the urinary tract and in particular of the kidneys and bladder is described. The results in a series of 10 patients (9 with hypernephroma and 1 with a carcinoma of the bladder) are analyzed and the advantages as well as the dangers of this method in the management of operable and nonoperable tumours of the kidneys are discussed.

Adenocarcinoma