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C Dorsey

Publications and source records attributed to C Dorsey.

9 recordsLinked to original sources
PubMed1995

Ultrastructure of the ventral sucker of Schistosoma mansoni cercaria.

The ventral sucker of Schistosoma mansoni cercaria is a cup-shaped structure that is attached to the ventral surface of the organism by a homogeneous connective tissue that surrounds the acetabular glands. The sucker consists of an extensive complex of circular and longitudinal muscles. The longitudinal muscles extend outward in a radial pattern to form the cup of the organ. Intermingled with the muscles are nerve bundles and subtegumental cells (cytons). Dendritic nerve fibers connect to sensory papillae which are found on the surface tegument. Two types of sensory papillae are present: a commonly found unsheathed uniciliated papilla, and a previously unidentified tegumental encapsulated structure. Tegument with spines covers the ventral sucker, although the tegumental encapsulated sensory papilla lacks spines.

Animals↗
PubMed1995

Cyton II: a subtegumental cell type in the cercaria of Schistosoma mansoni.

In Schistosoma mansoni cercaria, an aggregate of subtegumental cells is found in a small, dorsoanterior area of the body (middivision). These cells are nestled between two laterally positioned flame cells and the muscle that delimits the anterior end of the body, and the anterior end of the central ganglion. This highly amorphous cell type, designated as cyton II, has a heterochromatic nucleus and a cytoplasm that is elaborated into coarse, tortuous processes. Its cytoplasm contains ribosomes, mitochondria, sparse amounts of endoplasmic reticulum, and two types of circular-to-oval concentric membranous bodies. One type has an electron-dense core and measures 200-250 nm on the short axis, and the other is completely membranous and measures 100-125 nm on the short axis. The cell body of cyton II communicates with the tegument that covers a small, dorsoposterior area of the anterior organ (oral sucker); however, we could not confirm a tegumental connection with the body division. When cercariae transform into schistosomules, the concentric membranous bodies of cyton II migrate into the anterior organ's tegument via cytoplasmic processes of the cell. The major function of previously described cells that have similar membranous bodies is to supply additional membranes to the outer tegument during development into an adult worm. A multilaminated outer membrane is an adaptation to the survival of the schistosomule and adult worm in the bloodstream of the vertebrate host (Hockley amd McLaren ['73]). The presence of membranous bodies from cyton II in the tegument does not confirm that this cell type participates in the formation of multilaminated membranes. Its precise function remains to be determined.

Animals↗
PubMed1989

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Allied Health Personnel↗
PubMed1988

Comparative single-dose kinetics and dynamics of lorazepam, alprazolam, prazepam, and placebo.

Thirty-nine healthy volunteers received single oral doses of either alprazolam (1 mg), lorazepam (2 mg), prazepam (20 mg), or placebo in a randomized, double-blind, parallel group study. Plasma drug concentrations, subjective self-ratings, and the digit symbol substitution test (DSST) were evaluated during 24 hours after dosage. Alprazolam was absorbed rapidly and produced correspondingly rapid sedation and impaired DSST performance. These effects also resolved rapidly, being similar to placebo by 4 to 6 hours after dosage. Sedative and DSST-impairing effects of lorazepam were of slower onset but longer duration than those of alprazolam. After oral prazepam, appearance of desmethyldiazepam in plasma was slow, with minimal sedative and DSST-impairing effects. Twenty-four hours after dosage, both alprazolam and lorazepam significantly impaired recall of a list of 16 words learned previously 3 hours after dosage. Thus benzodiazepines with approximately equivalent clinical anxiolytic properties may have different sedative, performance-impairing, and amnesic profiles after single doses in healthy volunteers; these differences are explained at least in part by pharmacokinetic variations.

Adult↗
PubMedDate not supplied

Adult sickle cell patients' perceptions of nurses' caring behaviors.

Sickle cell disease (SCD) is a life-long, acutely painful, chronic illness. This study was conducted to explore differences in perceptions of nurses' caring behaviors between adults with SCD and adults with general medical conditions and the differences in perceptions of nurses' caring behaviors between men with SCD and women with SCD. Watson's (1988) Theory of Human Caring provided the conceptual framework. In this descriptive, correlational design, convenience sampling was used to obtain 29 adults with SCD and 34 adults with other medical conditions. The mean age for adults with SCD was 35.8, and on average they reported four hospitalizations per year. The mean age for the general medical patients was 48.9, and they averaged two hospitalizations per year. Instruments used in this study were a demographic data form and the Caring Behavior Assessment, modified for use in this study. The instruments were distributed through support groups using the snowball technique. Data were analyzed using descriptive statistics and independent t-tests. Participants with SCD reported lower satisfaction with nurses' caring behaviors than those with other medical conditions (t = 2.19, p = .03). Women with SCD reported lower satisfaction with nurses' caring behaviors than men with SCD (t = 2.91, p = .01).

Adult↗