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Biomedical subjects

C Durand

Publications and source records attributed to C Durand.

At least 91 records · Page 5Linked to original sources
PubMed1990

[Maprotiline poisoning in an eleven-month-old infant].

The authors report the case of an eleven-month old infant who was given maprotiline and clobazam. He was found in coma state and suffered from convulsions, that were treated with phenobarbital. The electrocardiogram showed a right bundle branch block and a left anterior hemiblock over 72 h. The child then recovered without sequelae.

Anthracenes↗
PubMed1989

A crosslinguistic investigation of vowel formants in babbling.

A cross-cultural investigation of the influence of target-language in babbling was carried out. 1047 vowels produced by twenty 10-month-old infants from Parisian French, London English, Hong Kong Cantonese and Algiers Arabic language backgrounds were recorded in the cities of origin and spectrally analysed. F1-F2 plots of these vowels were obtained for each subject and each language group. Statistical analyses provide evidence of differences between infants across language backgrounds. These differences parallel those found in adult speech in the corresponding languages. Implications of an early build-up of target-language-oriented production skills are discussed.

Algeria↗
PubMed1989

[Peptidoglycan modification of Staphylococcus aureus P18 strain after use of 6 active antibiotics on the bacterial wall].

Six antibiotics active on the cell-wall were tested against a methicillin resistant Staphylococcus aureus P18 strain at the start of exponential growth rate. The concentration was four-fold the MIC determined in a non-hypersaline liquid medium. The peptidoglycan amino-acid content of the various cell wall samples was determined. An antibiotic-free S. aureus P18 and the methicillin-sensitive Cowan I. S. aureus strain were used a controls. Beta lactam antibiotic treatment, oxacillin and cephalothin, induced an increase of alanine content which suggests that only secondary-transpeptidation did not occur. Similar results were obtained using vancomycin. Amino-acid content was not modified by bacitracin, which is in agreement with the results expected. The results obtained for fosfomycin and cefamandole were not easy to interpret.

Anti-Bacterial Agents↗
PubMed1988

Percutaneous balloon dilatation of calcific aortic valve stenosis: anatomical and haemodynamic evaluation.

Two groups of elderly patients with calcified aortic stenosis were treated by balloon dilatation. In group 1, the valve was dilated just before surgical replacement of the valve. The valvar and annular changes occurring during dilatation were examined visually. In 20 of the 26 patients in this group there was no change. In the six remaining patients mobilisation of friable calcific deposits (1 case), slight tearing of the commissure (4 cases), or tearing of the aortic ring (1 case) were seen. Dilatation did not appear to alter valvar rigidity. In 14 patients (group 2) the haemodynamic gradient across the aortic valve was measured before and immediately after dilatation and one week after the procedure. Dilatation produced an immediate significant decrease of the aortic mean gradient and a significant increase of the aortic valve area. Eight days later the mean gradient had increased and the aortic valve area had decreased. Nevertheless there was a significant difference between the initial gradient and the gradient eight days after dilatation. The initial aortic valve area was also significantly larger than the area eight days after dilatation. The aortic valve gradient rose significantly in the eight days after dilatation and at follow up the gradients were those of severe aortic stenosis.

Aged↗
PubMed1988

[DSP 4, a neurotoxic agent that destroys noradrenergic endings, selectively increases "expectancy" in the cat].

Cats were treated with DSP 4, a neurotoxic agent known to destroy central noradrenergic endings. A significant increase was subsequently noticed in the amount of time spent by the treated animals in an attitude of "expectancy", i.e. of motionless waiting for an "event to occur". They even developed this attitude when no such real situation existed. Concomitantly, an increase was noticed in the power of the 14 Hz electrocortical rhythms recorded over the somatic sensory cortex. These patterns, designated as "mu" rhythms, had previously been shown to characterize this particular type of attentive state. The present data tends to confirm our previous hypothesis, that immobile expectancy and its accompanying electrocortical pattern are under a noradrenergic inhibitory control.

Animals↗
PubMed1988

[Neural complications of injuries of the pelvis].

5 cases of serious neurological complications of pelvic trauma are reported. All consisted of lesions of the lumbo-sacral plexus. The course is similar to that seen in severe forms of untreated brachial plexus lesions since recovery is always very slow and very incomplete. No curative methods of management were used in the series described. Only secondary palliative surgery was carried out.

Adolescent↗
PubMed1988

[Fracture of the acetabulum].

Severe trauma of the acetabulum is uncommon in children. However, it must be remembered that these apparently benign lesions can be responsible for serious complications. In a group of 31 children under the age of 16 years presenting with such lesions, 12 already had an adult type skeleton. Amongst the remaining children, 15 presented with fractures or fracture-dislocations of the acetabulum and 4 presented with marginal avulsions of the acetabular ridge. Two epiphysiodeses of the Y cartilage were observed, one in a 2 year old child, revealed by acetabular dysplasia at the age of 8 years, and the other in a 10 year old child which did not have any serious consequences. Three of the 4 cases of marginal avulsion were complicated by intra-articular incarceration, 2 of which were initially missed. Secondary surgical treatment achieved good functional recovery, but left radiological sequelae in the form of coxa magna.

Acetabulum↗
PubMed1987

Anterograde percutaneous transseptal valvuloplasty in a case of severe calcific aortic stenosis.

The retrograde catheterization and percutaneous dilatation of calcific stenotic aortic valves is not always possible in elderly patients. We report the case of a 76-year old woman admitted with severe aortic stenosis in whom it was impossible to reach the left ventricle retrogradely. This led us to attempt percutaneous aortic valvuloplasty using a transseptal anterograde approach. The Mullins transseptal sheath catheter was advanced into the left ventricle and a 7 F catheter containing a long guide wire (400 cm) passed through the sheath. The flexible end of the guide wire was advanced through the aortic valve anterogradely and an angled wireloop retriever used to catch the flexible end of the guide wire and to draw it out of the body through the left femoral artery. A 7 F balloon catheter was introduced percutaneously over the long guide wire and allowed dilatation of the interatrial septum and femoral vein. A 8 F Schneider-Grüntzig catheter (80 mm) length, 19 mm diameter when inflated) was inserted anterogradely through the aortic valve over the guide wire without difficulty and the balloon catheter was inflated to a pressure of 6 atmospheres with a 30 seconds inflation-deflation cycle. Before the procedure the mean aortic valvular gradient was 114 mmHg and the aortic valve area was 0.30 cm2. After the procedure the mean aortic gradient had fallen to 60 mm Hg and the valve area had risen to 0.90 cm2. These results are comparable to those expected using the more usual retrograde balloon dilatation of the aortic valve.

Aged↗
PubMed1986

[Transluminal dilatation of occluded coronary arteries. Value of retrograde opacification of the occluded vessel by the contralateral artery].

The authors report the results of 8 cases of percutaneous transluminal coronary angioplasty of occluded arteries: the artery concerned was the proximal segment of the left anterior descending artery in 5 cases and the proximal segment of the right coronary artery in 3 cases. All patients had unstable angina with a very positive exercise stress test. The conservation of viable myocardium was the result of an excellent collateral circulation from the controlateral vessel in all patients. In 7 out of the 8 cases, the guide wire and dilating balloon were correctly positioned by opacifying the distal segments of the occluded artery by injection of contrast into the controlateral artery. Almost simultaneous injection of the occluded and controlateral vessels allowed evaluation of the length of the occlusion. Controlateral opacification disappeared immediately after adequate recanalisation to reappear during inflation of the balloon. These cases show that in patients with chronic coronary occlusion, opacification of its distal segments by injection of contrast into the controlateral vessel seems to be helpful and without risk to the patient.

Adult↗
PubMed1986

[Respiratory syncytial virus infections in newborn infants].

Twenty-three of 23 neonates were contaminated in the course of an outbreak of respiratory syncytial virus (RSV) in a neonatal care unit. Symptoms among 22 infected symptomatic infants included rhinitis (n = 21), dyspnea (n = 19), cough (n = 17), apnea (n = 5), seizures (n = 3), fever (n = 3). Five patients presented with severe respiratory distress. The occurrence of non-obstructive apnea was significantly correlated with a history of respiratory disease, RSV infection during the first 15 days of life and the severity of lower respiratory tract RSV infection.

Cross Infection↗
PubMed1986

A continuous hemofiltration system using sorbents for hemofiltrate regeneration.

Plasma ultrafiltrate obtained by glomerular filtration undergoes tubular modification which leads to the elimination of toxic substances, excess water and electrolytes, and consequently maintains homeostasis. Using normal urine and the substances it contains as a reference, we have developed a wearable device capable of replacing both the renal excretion function and maintaining fluid and electrolyte equilibrium in uremics within acceptable biological limits. Our device includes a hemofilter allowing continuous plasma ultrafiltration and sorbents obtained from a Redy sorbent cartridge to treat 85% of the ultrafiltrate, whereas 15% of this UF is rejected untreated. After calculating the quantity of ultrafiltrate (about 13 l) containing an amount of waste products of metabolism equivalent to 24-h urine elimination, we determined in vitro the amount of sorbent required to eliminate these waste products from the ultrafiltrate (e.g., 20 g of urea/day) and we have evaluated the quantities of other substances which must be replaced using a tailored diet. This extra-corporeal detoxification process was used in a uremic patient who had been on traditional hemodialysis for the past two years. The continuous treatment permitted maintenance of fluid and electrolyte equilibrium at the desired level and allowed rapid improvement of patient clinical status: elimination uf nausea, vomiting, diarrhea and edema, which had previously reappeared during the interdialytic periods, as well as a rapid decrease in heart size as ascites disappeared. In addition, the patient regained sexual drive and the ability to have an erection. In conclusion, traditional hemodialysis and hemofiltration techniques allow intermittent elimination of products retained by the body and reestablish nearly normal fluid and electrolyte balance.(ABSTRACT TRUNCATED AT 250 WORDS)

Adsorption↗