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Biomedical subjects

C E Casey

Publications and source records attributed to C E Casey.

27 records · Page 2Linked to original sources
PubMed1981

Availability of zinc: loading tests with human milk, cow's milk, and infant formulas.

Uptake of zinc with human milk, cow's milk, and four infant formulas investigated using a standard zinc loading test. Female subjects consumed 25 mg of zinc with the milk or formula, the amount of which was calculated to provide 5 gm of protein, after an eight-hour fast. Blood samples were taken prior to (base line) and at 30-minute intervals for three hours after consumption of zinc. Plasma zinc response was calculated as the area under the curve change in plasma zinc from the base line value, plotted against time over three hours. The plasma response with human milk was significantly greater (P less than .005) than with cow's milk and all the formulas. The response with cow's milk and a cow's milk-based formula was one third that with human milk; responses with a soy-based and two casein hydrolysate-based formulas were lower. These results are compatible with the concept, strongly suggested by indirect evidence, that the bioavailability of zinc with human milk is better than with cow's milk or infant formulas.

Animals↗
PubMed1980

Prostaglandins in human duodenal secretions.

Prostaglandins E1, E2 and F2 alpha were measured in duodenal secretions from two healthy, fasting male subjects. Secretions were collected by duodenal intubation prior to, and following, stimulation by secretin and cholecystokinin. Prostaglandins were measured with a radioimmunoassay technique. The ranges of concentrations found were PGE1: 2.4-110 ng/ml, PGE2: 0.004-1.51 ng/ml, and PGG2 alpha: 0.44-14.6 ng/ml.

Adult↗
PubMed1978

Copper, manganese, zinc, nickel, cadmium and lead in human foetal tissues.

1. Concentrations of copper, manganese, zinc, nickel, cadmium and lead were measured in samples of liver, kidney, brain, heart, lung, skeletal muscle and vertebral bone from forty foetuses of 23-43 weeks gestation. 2. Cu concentrations in the liver were up to 100 times those in other tissues, but only those in the brain showed a significant increase with gestational age. 3. Mn concentrations were similar in all tissues; the over-all range was 0.35-9.27 microgram/g dry matter (DM). 4. Concentrations of Zn in the liver were much higher than in other tissues and decreased with gestational age, whereas levels in skeletal muscle increased. 5. In all tissues Ni concentrations were within the range 0.04-2.8 microgram/g DM and levels in kidney and muscle decreased significantly with age. 6. Cd was detected in most of the tissue samples and concentrations were within the range 0.01-0.58 microgram/g DM. 7. Concentrations of Pb, where it was detected, varied from 0.1 to 2.4 microgram/g DM in the soft tissues and from 0.4 to 4.3 microgram/g DM in the bone samples.

Cadmium↗
PubMed1977

The content of some trace elements in infant milk foods and supplements available in New Zealand.

The concentrations of iron, copper, zinc, manganese, nickel, cadmium and lead are reported for milk foods and supplements offered to infants before the introduction of mixed feeding. Levels of most of the trace elements in samples of breast milk and homogenised cows' milk were within the ranges reported overseas. Most of the milk products should supply adequate amounts of iron, copper, manganese and nickel to the young infant although zinc intakes may be marginal. Concentrations of cadmium and lead were well below the maximum values permitted by law.

Animals↗
PubMedDate not supplied

Selenium in human tissues from New Zealand.

Selenium concentrations were measured in tissue samples obtained at autopsy from 45 New Zealand residents aged 4 months to 74 yr. Materials included liver, kidney cortex, skeletal muscle, heart, lung, and spleen. Samples of liver and brain were obtained from 16 fetuses (gestational ages, 27-42 wk). Except for kidney cortex, which contained high levels, concentrations of selenium were similar to those reported in other low-selenium areas, and lower than values obtained in selenium-adequate localities.

Adolescent↗