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Biomedical subjects

C E Hugkulstone

Publications and source records attributed to C E Hugkulstone.

28 records · Page 2Linked to original sources

Blue versus white stimuli in ocular hypertension with the Friedmann Mark 1 Visual Field Analyser.

Fifty eyes of fifty patients with ocular hypertension had their visual fields tested on a Friedmann Mark 1 field analyser whilst wearing a Wratten 47B blue filter in a spectacle frame. All had normal visual fields to a white stimulus. Use of a scoring system with the blue field identified 11 patients (22%) with ocular hypertension as abnormal. The scores from this subgroup were indistinguishable from a group of subjects with early glaucomatous field loss, whilst the remaining scores were similar to normal subjects. These two subgroups of ocular hypertensive patients were similar in age and intraocular pressure. The use of a blue filter in front of the eye may offer a simple test to identify a subgroup of patients with ocular hypertension who are at increased risk of developing field loss.

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Use of a bandage contact lens in perforating injuries of the cornea.

Four cases of perforating corneal injuries as a result of work-related injuries are presented. All were managed with a bandage contact lens and surgical intervention was avoided. Topical pilocarpine was used to free incarcerated iris in two cases. All patients received a course of broad-spectrum systemic antibiotics, and also used topical preservative-free chloramphenicol for the duration of contact lens wear. No lens related complications occurred. Final unaided visual acuities were the same or better than at presentation.

Adult↗

Use of a blue filter in visual field analysis.

One hundred and twenty seven eyes of 127 patients were studied by means of a Kodak 47B Wratten blue gelatin filter in conjunction with the Friedmann Mark 1 visual field analyser. There were 49 patients in the normal group, 50 patients in the ocular hypertension group, and 28 patients in a group with early glaucoma. A simple scoring system did not show a useful difference between these three groups. However, use of a derived threshold value for each target group designated by the letters B to P (giving selective blue field scores) differentiated between normal subjects and those with early glaucomatous field loss. When used with a calculated upper limit of normal to give a specificity of 96%, this test had a sensitivity of 64%. Of the ocular hypertension group 22% gave abnormal results in comparison with normal persons. This simple adaptation to the Friedmann protocol may aid the ophthalmologist in the detection and confirmation of early glaucoma.

Evaluation Studies as Topic↗

Changes in keratometry following trabeculectomy.

The results of keratometry following trabeculectomy are presented. In contrast to the effects of wound gape after cataract extraction, trabeculectomy produces a reduction in the vertical corneal radius. An initial corresponding increase in horizontal radius is found immediately postoperatively, but this is not apparent by two and seven weeks after surgery. A possible explanation for these findings is proposed.

Aged↗

Standard and long duration repeat argon laser trabeculoplasty.

A retrospective survey was performed on 22 patients with chronic simple glaucoma who had undergone a single repetition of argon laser trabeculoplasty. Two groups were identified who had received treatment with either 0.1 or 0.2 sec duration. The 0.2 sec group showed a reduction in the medications used, in addition to a comparable fall in intra-ocular pressure to the 0.1 sec group, and had a lower rate of drainage surgery. These findings may have arisen because of the higher energy delivered as a result of the longer duration employed. However, there are risks of repeating argon laser trabeculoplasty: one patient in the 0.2 sec group developed a rise in intra-ocular pressure of 15 mmHg following the repeat treatment, and required drainage surgery one month later.

Aged↗

Argon laser trabeculoplasty with standard and long duration.

A prospective study of 0.1 sec and 0.2 sec duration argon laser trabeculoplasty was undertaken in 33 patients with chronic simple glaucoma. Patients were randomly allocated to receive 0.1 sec trabeculoplasty to the eye and 0.2 sec trabeculoplasty to the other. No difference was found in the fall in intra-ocular pressure or in glaucoma control between the two durations over the six months of the study. However, 0.2 sec argon laser trabeculoplasty was reported to be more uncomfortable of 60% of patients.

Aged↗

The effects of different energy levels in argon laser trabeculoplasty.

In a retrospective survey of 143 eyes of 143 patients with chronic open-angle glaucoma, 0.2 second argon laser trabeculoplasty was found to produce a greater decrease in intra-ocular pressure, especially at higher initial values, and was associated with a reduction in the medications used. In addition, fewer patients required further intervention (repeat trabeculoplasty or drainage surgery) compared with those undergoing 0.1 second trabeculoplasty. This effect may have occurred because of the difference in the mean energy delivered between the two groups, which arose chiefly as a result of the duration employed.

Follow-Up Studies↗

Uncomplicated phacoemulsification and first-day review: the patient's perspective.

PURPOSE: To evaluate patients'opinions regarding first-day review following uncomplicated phacoemulsification. METHODS: A prospective questionnaire-based survey was conducted on consecutive patients at the time of listing for day-case phacoemulsification. Data collected included demographic details, proposed anaesthetic technique, first or second eye surgery and postcode. Statistical analysis was undertaken with the unpaired t-test, the chi2-test with Yates' correction for small numbers or Fisher's exact test, and Kendal's rank correlation, as appropriate. RESULTS: 100 patients (59% female; mean age 74.2 (12.6) years) were recruited. 87% preferred to return to hospital for their first-day review. This result was not significantly affected by sex, proposed anaesthetic technique, first eye surgery or postcode area. Only patients < 65 years old preferred not to return (p<0.02). CONCLUSIONS: In this population, patients preferred to return for first-day review following uncomplicated phacoemulsification. There may be some variance in the opinions of surgeons and patients regarding this issue, and the patient's preferences should be taken into account to provide optimum quality of care.

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