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Biomedical subjects

C E Koop

Publications and source records attributed to C E Koop.

At least 19 recordsLinked to original sources
PubMed1991

Single-use syringes.

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Acquired Immunodeficiency Syndrome↗
PubMed1991

Why CME?

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Acquired Immunodeficiency Syndrome↗
PubMed1989

The silver anniversary.

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Anniversaries and Special Events↗
PubMed1989

Cryptorchidism, orchiopexy and infertility: a critical long-term retrospective analysis.

We assessed the fertility of 40 patients who underwent orchiopexy between 1950 and 1960. Testicular biopsies also had been performed at operation, a practice exceptional for the era. Of 23 patients with unilateral undescended testes who attempted to have children 20 (87 per cent) were successful. In contrast, only 3 (33 per cent) of 9 patients with bilateral undescended testes fathered children. Over-all sperm counts in 16 patients were low but they were not predictive of paternity. Testicular biopsy specimens were reviewed and the fertility index was determined. In most cases a good correlation was found between histological status and paternity status.

Adult↗
PubMed1989

Responding to the patient who has AIDS.

Acquired immune deficiency syndrome (AIDS) has burrowed its way into the fabric of American society. Unless we recognize the extensive and permanent damage it can do there, we are going to lose more than human lives. The tradition of medicine is that physicians do not abandon the sick, whoever they are and whatever they have done, and overall Americans can be proud of the way we have successfully faced the challenge of fairness. Now, however, we need to focus on the "professional will to respond." Doing so means providing support to the individual physician, ensuring that everyone in the profession is informed about AIDS and makes all necessary adjustments of behavior and commitment. The medical profession must lead the public and other health professionals in responding morally, ethically, personally, and professionally to the AIDS epidemic. Otherwise, physicians will be relegated to the sidelines as the electorate, courts, and government agencies debate and adjudicate AIDS issues.

Acquired Immunodeficiency Syndrome↗
PubMed1986

A mouse model for the study of necrotizing enterocolitis.

A mouse model for the study of necrotizing enterocolitis is presented. It is a model of temporary intestinal ischemia and consists of occluding both superior mesenteric vessels with a bulldog clamp for varying periods of time. The resultant lesions resemble the intestinal lesions seen in necrotizing enterocolitis in respect to the gradual development of the necrotizing lesions and their patchy distribution. We also studied the effect of intravenous saline and low molecular weight dextran in preventing the development of these ischemic lesions. In moderate ischemia, saline and dextran show a similar protective effect, and in severe ischemia, both show a protective effect, with dextran being more effective than saline.

Animals↗
PubMed1979

Sequelae of prolonged ventilatory support for pediatric surgical patients.

The evolution of intensive prolonged respiratory support has been a major development in improving survival in the critically-ill child. That intensive respiratory support can be maintained for prolonged periods of time even in the home with survival of good babies is the subject of this report. In a 3-yr period, 2112 surgical patients were admitted to intensive care facilities with an over-all survival of 95%. Ventilatory support was required in 368 (17.4%) of these children, and survival in this group was 75.3%. Prolonged mechanical ventilation was necessary in 13 of the 368 children (3.5%) for a mean support time of 359 days (range 101 to 1095). Of these 13 children, 4 died while hospitalized (30.8%), and 3 died subsequently after being discharged (23.1%) for a total mortality of 53.8%. However, 6 children (46.2%) survive, 3 free of ventilatory support and 3 being weaned from their machine at home. The greatest cost in this expensive program was delivered to the survivors and psycho-social and developmental data confirm that these children are good babies with favorable long-term prognoses.

Child↗