Tirandamycin, a new antibiotic isolation and characterization.
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Anti-Bacterial Agents↗
Biomedical subjects
C E Meyer
Publications and source records attributed to C E Meyer.
A polypeptide antibacterial agent isolated from Trichoderma viride.
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Amino Acids↗
U-12,241, a new antibiotic. II. Isolation and characterization.
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Anti-Bacterial Agents↗
U-21,963, a new antibiotic. II. Isolation and characterization.
The isolation and characterization of antibiotic U-21,963 are discussed. This compound is a highly unsaturated monobasic acid with the molecular formula C(9)H(7)NO(3). The molecular weight is 177. It is dextrorotatory, [alpha](D) = +138 degrees , and has a pK(a) of 5.1. The ultraviolet absorption spectrum, which showed a maximum at 223 mmu (epsilon = 15,115), indicates unsaturation alpha-beta to the carboxyl group, and the infrared spectrum suggests the presence of an acetylenic group. Explosive decomposition of U-21,963 at 97 C conforms with the latter. U-21,963 is relatively insoluble in water, but readily soluble in ethyl alcohol, acetone, and halogenated hydrocarbons.
Anti-Bacterial Agents↗
New antibiotics produced by Streptomyces caelestis.
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Anti-Bacterial Agents↗