PubMed Health⌕ Search

Biomedical subjects

C E Moon

Publications and source records attributed to C E Moon.

4 recordsLinked to original sources

The presence of luteinized unruptured follicle syndrome and altered folliculogenesis in rats with surgically induced endometriosis.

OBJECTIVE: Our purpose was to determine in the rat model whether endometriosis could influence ovarian function by altering oocyte release or folliculogenesis. STUDY DESIGN: We histologically examined the ovaries of reproductively cycling rats with (n = 16) and without (n = 10) surgically induced endometriosis. The rats in these two groups were further subdivided into unilaterally ovariectomized or ovarian-intact groups. Serial sections of ovaries were examined, and follicular development and frequency of luteinized unruptured follicles were determined. RESULTS: A significant tenfold increase in the number of luteinized unruptured follicles was observed in the ovaries from rats with endometriosis (2.7 per rat) compared with unoperated and sham-operated control groups (overall mean 0.26 per rat, p < 0.05). Additionally, ovaries from unilateral ovariectomized animals with endometriosis contained four times as many luteinized unruptured follicles (four per rat) as did the ovaries from bilaterally ovarian-intact rats with endometriosis (1.40 per rat, p < 0.01). Fewer follicles were present in rats with endometriosis (180 follicles per ovary) than in control rats (231 follicles per ovary, p < 0.05). CONCLUSION: In the rat model the presence of ectopic endometrium is associated with an increased frequency of luteinized unruptured follicles and altered follicular development.

Animals↗

Sustained attentional and disattentional abilities: differences between low and highly hypnotizable persons.

Relations between sustained attentional and disattentional abilities and hypnotic susceptibility (Harvard Group Scale of Hypnotic Susceptibility: Form A; Stanford Hypnotic Susceptibility Scale: Form C) were examined in 38 low (0-3) and 39 highly (10-12) hypnotizable college students. Highs showed greater sustained attention on Necker cube and autokinetic movement tasks and self-reported greater absorption (Tellegen Absorption Scale) and extremely focused attentional (Differential Attentional Processes Inventory) styles. Hypnotizability was unrelated to dichotic selective attention (A. Karlin, 1979) and random number generation (C. Graham & F. J. Evans, 1977) tasks. Discriminant analysis correctly classified 74% of the lows and 69% of the highs. Results support H. J. Crawford and J. H. Gruzelier's (1992) neuropsychophysiological model of hypnosis that proposes that highly hypnotizable persons have a more efficient far frontolimbic sustained attentional and disattentional system.

Adult↗

Effects of the menstrual cycle on the human acoustic reflex threshold.

Contralateral acoustic reflex thresholds (ARTs) were determined daily in 10 normal women and 10 men, aged 18-24, in response to a broad-band noise, over a 32-day period. Mean ARTs for men vs women over the period differed by only 1.55 db, but for women a stimulus level of about 6 db more was required to elicit ART over Days 1-6 of the menstrual cycle than over Days 7-26 (p less than .01). There was furthermore an increase in sensitivity in the luteal phase (Days 15-19) of the cycle. It appears that the changes in ART throughout the cycle mirror, and may reflect, concomitant changes in the hormonal (estrogen and progesterone) levels. Changes in ART over the cycle may thus be explained by hypothesizing that the ART is an aspect of sensorineural behavior affected by hormonal concentrations to which a number of other auditory phenomena are known or thought to be related.

Acoustic Stimulation↗