THE EPIDEMIOLOGIC BONUS.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to C E PALMER.
Explore the source record for details and available documents.
The frequency of infection with the fungus Histoplasma, as judged by the results of skin tests with histoplasmin, varies widely from county to county across the USA and even over very short distances within some counties. Differences between various segments of the population, such as between Negroes and whites, living in one particular community are therefore difficult to interpret, as they might represent the effect of differences in ecological rather than in demographic factors within the community. Since the pertinent ecological differences could, however, be expected to balance out if a large number of communities were sampled, results of histoplasmin skin tests among Negro and white Navy recruits from 37 different communities are compared in the present report. The prevalence of reactors to histoplasmin ranges from zero to over 90% in residents of the different geographical areas, indicating wide variations in the ecological conditions affecting the growth and dissemination of the fungus, yet comparisons of results in Negroes and whites indicate that the factors influencing infection and sensitization of man appear to bear equally on both racial groups. Results with tuberculin PPD-S and the Battey PPD antigen in the same groups of recruits are included to supplement the results with histoplasmin.
In most countries there have been signs in recent years of an accelerated decline in tuberculosis, but only the most superficial knowledge exists of what underlies the remarkable changes. It is therefore imperative to document the changing picture of tuberculosis by means of parameters that are not only descriptive but will also serve as guidelines for the development of methods to eradicate the disease.The authors describe the present system of tuberculosis reporting and control in Denmark, where the requisite conditions for obtaining meaningful statistics are, to a large extent, fulfilled, discussing its potentialities for depicting the forces behind the recent changes and pointing out its inherent deficiencies.The advantages of the Danish system, in which rates for the prevalence and incidence of respiratory tuberculosis are broken down into those for new cases and those for relapses, are stressed, as is the significance of the recently introduced practice of reporting cures and thus obtaining cure rates on a nation-wide scale.As an indicator of the lethal effect of tuberculosis in a country, the mortality rate suffers from several limitations, which will play an increasingly important role as the downward trend in tuberculosis continues. The authors suggest that a more objective measure than the specific mortality rate would be the so-called "lethality index" - an index based on all deaths occurring among persons with active tuberculosis, irrespective of whether they were attributed directly to the disease.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.