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Biomedical subjects

C Ellinger

Publications and source records attributed to C Ellinger.

13 recordsLinked to original sources
PubMed1986

[The action of phenylmercuriacetate and nitrate in combined application in rats: the thyroid gland, liver enzymes and morphologic findings in the brain and kidney].

Rats were exposed to nitrate (NO3-) in drinking water, to phenylmercuryacetate (PMA) by gavage and to NO3- and PMA together during 4 different experiments. PMA impaired kidneys, NO3- thyroid gland, and NO3- and PMA together both organs. In the last case a synergistic effect on the thyroid gland was shown. The lowest effective concentration of NO3- was 40 mg/l. It resulted in histomorphological changes of the thyroid epithelial cells. That low effective dose of NO3- and possible synergistic effects should give a further impulse to take into consideration not only a low iodide intake but also goitrogenic environmental chemicals when evaluating the endemic goitre prevalence.

Animals↗
PubMed1985

[Hematologic changes in rats following exposure to dichlorvos].

Two different experiments on rats were carried out: an acute intoxication causing clinical symptoms and a subchronical intoxication without any symptoms. After the acute experiment an increase of hemoglobin- and hematocrite values as well as of the mean corpuscular hemoglobin concentration was found. These differences are interpreted to be an increased erythropoiesis after hypoxia. Following the subchronical experiment the parameters mentioned above had decreased. These results linked up to anisocytosis, poikilocytosis and/or polychromasia in 30% of the treated animals and allow to assume a disorder of erythropoiesis. The results require to take in consideration a prophylactic hematological survey of long-term exposed people.

Animals↗
PubMed1985

Enzyme activities after in vitro and in vivo application of dichlorvos.

The pesticide dichlorvos inhibits not only cholinesterase but also alkaline phosphatase, lactate dehydrogenase and glutamate dehydrogenase competitively. A mixed type inhibition of glutamic-oxaloacetic transaminase is in contrast to the increased activity of glutamic-pyruvic transaminase after dichlorvos application. The activity of leucine aminopeptidase is not affected by the substance. After administering rats an acutely toxic dose of dichlorvos (70 mg per kg b.w.) in vitro-inhibitions other than that of cholinesterase could not be found.

Animals↗
PubMed1984

Cephalometric evaluation of the changes in patients wearing complete dentures. A ten-year longitudinal study.

This study analyzed the longitudinal cephalometric head films of 37 edentulous patients over a 10-year period. The purpose of the investigation was to document changes within the craniofacial complex, residual ridge resorption, and position of the dentures. The changes were correlated with the following variables: age, sex, skeletal pattern, number of years edentulous, technique of denture fabrication, and nighttime wear of the dentures. Findings in this study suggest the following. The maxillae and the mandible showed sagittal spatial counterclockwise displacement. Complete dentures exhibit a counterclockwise rotation and forward movement. Soft tissue seating is more important than alveolar ridge resorption in the positional changes of complete dentures. Variation in denture techniques had no influence on the observed changes. Artificial porcelain teeth did not show a measurable amount of attrition during the 10-year observation period. Observed changes were not significantly affected by variables such as sex, years edentulous, nighttime wear, or skeletal pattern. Two exceptions were that the skeletal pattern affects prognathism and number of years edentulous affects mandibular ridge resorption.

Adult↗
PubMed1984

[Spectrophotometric evaluation of hemolysis tests].

A quantitative spectrophotometric method for measuring the hemolysis degree of PVC-biomaterials by potassium hexacyanoferrate (III) and potassium cyanide is presented. By means of this method the physiological valuation of biomaterials proved more exact as to their contents of hemolytically acting substances. In order to define the maximum permissible degree of hemolysis from biomaterials further studies will be necessary. UV- and IR spectrograms of the 70 degrees C and 121 degrees C extracts from biomaterials indicated the presence of substances not yet identified till now. These substances couldn't be ascribed any specific biological effects. An extraction at 121 degrees C is recommended in order to detect hemolytically acting substances.

Biocompatible Materials↗