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Biomedical subjects

C Esley

Publications and source records attributed to C Esley.

7 recordsLinked to original sources

[Endoscopic treatment of acute pancreatitis of biliary etiology].

23 patients with acute biliary pancreatitis were treated with endoscopic papillotomy and extraction of bile duct stones. 12 suffered on an acute moderate and 11 on an severe pancreatitis in the classification of Glasgow. The patients were between 45 and 92 years old. 19 had an evolution without complications, 2, who also had an acute cholangitis, had a slow but good evolution. 2 died due to a septic shock and cardio-respiratory failure.

Aged↗

Primary sclerosing cholangitis.

Thirty patients, 18 males and 12 females, with PSC have been studied between 1972 and 1986. In nine PSC was associated with ulcerative colitis (30%), in 4 with Crohn's disease (13%) and 17 were free of any chronic bowel disease. Four of these 17 were siblings. Alkaline Phosphatase, Gamma GT, total bile acids and 7-alpha-hydroxilated bile acids were elevated in all patients. In 14 patients plasma and urinary copper as well as ceruloplasmin were studied, showing the copper in all cases and ceruloplasmin in 10 cases elevated, 4 were normal. By means of cholangiography alterations of the extrahepatic ducts, the intrahepatic ducts, and both the intra- and extrahepatic ducts were seen in 13%, 27% and 40% of the cases, respectively. Alterations of the pancreatic duct were observed by pancreatography in 21% of cases. 40% of the PSC-patients had also a Sjögren's syndrome, while 3% were associated with diabetes mellitus Type I and II, psoriasis and red lichen planus, iridocyclitis and hepatic hemangioma.

Adult↗

Primary sclerosing cholangitis.

Primary sclerosing cholangitis was diagnosed in 6 patients (4 men and 2 women), with ages ranging from 33 to 71 years. Four of them had ulcerative colitis, with an evolution from 8 to 21 years, the other two had Crohn's disease with 2 and 3 years of evolution. 66% of the patients had pain in the right upper quadrant; 50% complained of itching, 33% presented with fever, jaundice, weight loss and hepatomegaly and 16% had splenomegaly. 50% of these patients were diagnosed as having Sjörgren's syndrome. Alkaline phosphatase and gamma GT were elevated in 100% of the cases; SGOT and SGPT were slightly elevated in all cases; bilirubin was elevated only in 50% of the cases. Cholelithiasis was found in 2 patients with Crohn's disease and 1 patient with ulcerative colitis. All were subjected to laparoscopy. 2 of them were diagnosed as having persistent chronic hepatitis and the remaining patient had hepatic fibrosis. ERCP revealed alterations in the intrahepatic ducts and there was stenosis of the end of the common bile duct in one of them. The most frequent histological findings were periportal reactions with lymphocytes, plasma cells of macrophages, and periductal fibrosis with obliteration of the canaliculae.

Adult↗

[Sclerosing treatment of esophageal varices].

Sixty-five patients with hepatic cirrhosis and esophageal varices were subjected to endoscopic sclerotherapy. Twelve patients were treated in the intervals between hemorrhages; 43 patients were treated after their first hemorrhage. The rate of survival in a 5 to 26 month period was 82%.

Esophageal and Gastric Varices↗