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C Estel

Publications and source records attributed to C Estel.

At least 19 recordsLinked to original sources

[The correlation of reduced amniotic fluid volume, placental maturity and morphologic placental changes in placental insufficiency].

A reduced quantity of amniotic fluid is diagnosed semiquantitatively in 41 pregnant women in the 38th to 40th week of gestation. In 21 cases, the birth of a mature hypotrophic child below the 10th weight percentile is registered. Sonographically, the placentas of the mature eutrophic children significantly more frequently show a grade III maturity and the placentas of the mature hypotrophic children a grade II maturity. In contrast to the values found in the placentas of eutrophic children and in the placentas with grade III maturity, a significantly decreased villous vascularization is determined in the placentas of hypotrophic children and in placentas with grade II maturity. The area of attachment of the placenta is 301 cm2 for the eutrophic children and 222 cm2 for the hypotrophic children. All findings are discussed and compared with the relevant data of the pertinent literature.

Amniotic Fluid

[The significance of morphologic placental findings in fetal distress].

The causes of fetal distress are analyzed in 50 cases, with special emphasis being placed upon placental insufficiency. Clinically, no cause can be found for the condition of danger to the fetus in 8 pregnant women. The surface of the villous vessels evaluated by morphometric methods is significantly decreased in 10 placentas. Of the 8 pregnant women without known cause of fetal distress, 3 cases were found to show reduced villous vascularization. The relevance of morphological examinations of the placenta in fetal distress is discussed.

Chorionic Villi

[Effect of defined body stress in pregnancy on the functional values of the maternal cardiovascular system and fetal heart rate].

Four healthy women are subjected to a defined physical training in the 22nd and 34th weeks of pregnancy. Systolic and diastolic blood pressures, maternal heart rate, respiratory quotient, oxygen pulse, tension-time index and oxygen partial pressure are determined. In addition, the fetal heart sounds are registered in the 34th week of pregnancy. Normal levels of cardiorespiratory function can be detected in three patients. Fetal heart rate is likewise unremarkable. A considerable rise in blood pressure during exercise in one women only and, moreover, two accelerations of a duration of 6 to 7 minutes and a frequency of 200 beats per minute are recorded on the fetal cardiogram. The influence of physical training on uteroplacental circulation during pregnancy is discussed considering the results reported in the pertinent literature.

Adult

[Morphometric mitochondrial studies in the placenta of early pregnancies following a normal course of pregnancy and in maternal diabetes mellitus].

89 electron micrographs from a diabetic placenta of the 8th week of pregnancy and from two normal placentas of the same period of gestation are investigated morphometrically. In the trophoblast mitochondria of the diabetic placenta the surface/volume ratio between the surface of the cristae and mitochondrial volume shows a statistically significant reduction as compared to the values in the normal placenta of the same period of gestation. The morphological changes of the placenta are being related to disorders of the regulation of the metabolic processes in diabetes mellitus in early pregnancy.

Blood Glucose

[Morphometric studies of the placentas of hypertrophic newborn infants].

In a total of 31 placentae from new-born children weighing between 4000 g and 4499 g at birth and in 64 placentae from new-born children with standard weight, the relative surface of the villous vessels and the relative volumes of the villous epithelium, of the stroma and of the villous vessels are determined by the morphometric method. These morphometric parameters, which are characterising the villous vascularization and the relative placental area of exchange, are slightly greater for the placentae from overweight children compared to the values of the control group. The oral glucose tolerance test performed on the 3rd puerperal day appears to be normal in all 31 test persons. 20 mothers are overweight and their average height is about 173 cm. The results of the present study are related to the corresponding literature.

Birth Weight

Studies on the ultrastructure of the term amnion in pathological pregnancy.

The ultrastructure of the amniotic epithelium at term was examined in cases of intrauterine growth retardation of the fetus and compared with amnions obtained from women with a clinically unremarkable pregnancy. In uterine growth retardation the amniotic cells exhibit a general deficiency of a series of functionally significant cell organelles. The RER is insufficiently developed, there is a diminution of the normally numerous free ribosomes as well as of those cell organelles which are involved in secretory function. A further atypical finding is the common lack of intercellular canals playing an important role in the transamniotic exchange of material. Besides this, a very poor development or a complete disintegration of the microfilamentous cytoskelet is generally noticed. The present findings give once again evidence for a very close relation between the structural appearance of the intercellular diffusion canals and the microfilamentous system. The results presented are suggestive of an amnion which is in a state of reduced secretory activity, additionally, due to the common lack of intercellular canals an inhibition of the interepithelial passage between the maternal and amniotic compartment cannot be excluded.

Amnion

[Lymphocyte transformation test with streptococcal antigens in newborn infants and their mothers].

Following streptococcal mitogens and antigens were tested in the lymphocyte transformation test with human cord blood and maternal blood: streptococcal M1- and M19-proteins, mucopeptide, erythrogenic toxins and additional phytohemagglutinin. There are no significant differences in the blastogenic response with the different mitogens and antigens in maternal and cord blood. The cord blood lymphocytes show the same degree of blastogenic reaction to the mitogens and antigens as the maternal lymphocytes, that may reflect the state of readiness for cellular immunological defence. The spontaneous incorporation of 3H-labelled thymidine into cord blood lymphoblasts is significant higher than in lymphoblasts of maternal blood.--The results of specific and unspecific stimulation by means of steptococcal antigens are discussed.

Adult

[Smoking in pregnancy].

Of a total of 1658 women, 11% had been smoking during pregnancy. The proportion of the prenatally dystrophic new-borns was statistically significantly higher in the group of smoking women compared to that of the non-smoking women.--Women smoking during gravidity have to be cared for by a risk service for pregnant women.

Birth Weight

[Genital carcinoma in pregnancy].

From 1949 to 1974 there had been found and treated 131 malignant genital tumours during pregnancy post partum and post abortum at the Clinic of Obstetrics and Gynaecology of the University of Jena. The 5-year rate of surival of cervical carcinomas was 59,6%. That is no difference to cases discovered outside of pregnancy. It is discussed the possible influence of pregnancy on the growth of cervical cancer.

Female

[Morphometric examinations of the uterus in puberty, pregnancy and climacteric].

The text deals with morphometric examinations of histological specimen of cervical and corporal parts of the uterus in puberty, pregnancy and menopause. The results show the different relations between muscular and connective tissue elements in corpus and cervix and point to significant differences in the composition of specific layers of uterine wall.

Adolescent

[Morphometric examinations of placenta in stillbirth].

A total of 10 placentas was examined morphometrically following fetal death in utero. In 8 placentas a reduced fetal vascular surface could be observed. In 2 cases the cause of death could be revealed neither clinically nor patho-anatomically, while morphometric investigations demonstrated considerable restrictions of the vascular surface of the villi. In addition to the usual histological placental diagnostics, the morphometric assessment of placentas is recommended.

Female

[Relationship between morphometric placental studies and clinical biochemical findings in EPH-gestosis].

The relative fetal vascular surface established morphometrically in 22 gestosis placentas was clearly decreased compared to normal placentas. An accordance between the result of the DHEA-S-tolerance test and the relative fetal vascular surface was demonstrable in parts only. On the other hand, we, too, are able to confirm the results described in the literature that the restrictions of the fetal vascular surface correlate with the increase of the gestosis index.

Adult