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C F Duggan

Publications and source records attributed to C F Duggan.

6 recordsLinked to original sources

Dysfunctional attitudes in depressed and recovered depressed patients and their first-degree relatives.

A series of depressed probands and their first-degree relatives were categorized as follows: (a) currently depressed; (b) recovered depressed; and (c) never-ill relatives. Their scores on a subscaled version of the Dysfunctional Attitude Scale (the DAS-24) were compared. The DAS total scores mirrored previous findings in that the total scores for recovered individuals returned to normal or near-normal levels. However, the dependency subscale scores remained elevated for the recovered depressed group. It is proposed that these results support the conclusion that self-report measures of cognitive vulnerability should focus on specific rather than global effects, if progress is to be made in the search for true vulnerability factors.

Achievement↗

Do different subtypes of hospitalized depressives have different long-term outcomes?

In 1965 and 1966, a consecutive series of 89 patients admitted to the Maudsley Hospital, London, England, with depressive illness were interviewed, and various personality questionnaires were administered; 18 years later, they were followed up and reinterviewed. Then, on the basis of the index data alone and without knowledge of their eventual outcomes, they were subtyped according to the Research Diagnostic Criteria, DSM-III, Newcastle Index, and Present State Examination diagnostic criteria. Patients who met the various subtype criteria at index were compared with those who did not in respect to their long-term outcome. Subtyping had little prognostic utility except for three endogenous criteria that were all associated with poor outcome. In addition, DSM-III melancholia had an interactive effect with the personality measure neuroticism, so that those melancholic patients who at index had high neuroticism scores were very likely to have a poor outcome.

Adolescent↗

Can future suicidal behaviour in depressed patients be predicted?

The determinants of suicidal behaviour over 18 years were examined in a series of 89 depressed in-patients, using index data on clinical features, personality, and history of past loss. Seven variables were selected from univariate analyses and their relationship with (1) the presence or absence, (2) frequency, (3) intent, and (4) medical threat of suicidal behaviour was then explored by generalised linear modelling. Severe dysphoria, past alcoholism and chronic physical illness were most predictive of suicidal attempting; however, different variables predicted the frequency, degree of intent and severity of medical threat of subsequent suicidal attempts. Thus, our results suggest that different aspects of long-term suicidal behaviour have different determinants.

Adolescent↗

Does recurrent depression lead to a change in neuroticism?

The hypothesis that recurrent or chronic depressive illness produces a long-term change in neuroticism was examined in a sample (N = 34) from a consecutive series of 89 depressed patients admitted to the Maudsley Hospital in 1965/6. The Eysenck Personality Inventory (EPI) was administered at the time of the index illness both when the patients were depressed and on recovery, and then again at follow-up 18 years later. The change in the neuroticism (N) score over the 18-year-period was compared in good and poor outcome groups defined variously by a global rating of outcome, frequency of episodes, extent of subsequent hospitalization and the presence or absence of subsequent chronicity. The mean N score for the sample as a whole did not change significantly over the 18 years, and no differential change in the N score was observed between any of the good and poor outcome groups. Thus, the hypothesis was not supported.

Adolescent↗

Does personality predict long-term outcome in depression?

In 1965/66, a consecutive series of 89 in-patients with depression were interviewed, given two personality tests (the EPI and LOI), and were accorded a score on a neurotic-psychotic continuum (DI). Eighteen years later, the series was followed up and the predictive power of the original data was determined. High neuroticism scores on the EPI on recovery and particularly when ill but referring to the pre-morbid state were associated with poor overall outcome and chronicity. High obsessional interference scores on the LOI on recovery were also associated with poor long-term outcome, impaired social adjustment, more time spent in hospital, and with the subsequent development of schizophrenic or schizoaffective episodes. High psychotic scores on the DI were also associated with poor long-term outcome, a greater length of time spent in hospital, and with bipolar affective disorder, and this effect was independent of the personality measures.

Adolescent↗