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Biomedical subjects

C F Loughran

Publications and source records attributed to C F Loughran.

At least 19 recordsLinked to original sources
PubMed2000

Saw tooth patello--femoral arthritis.

Four patients with an unusual form of patello-femoral arthritis are described. The characteristic feature of the condition is an erosive 'saw tooth' pattern characteristically seen on both sides of the joint. Radiologically, this pattern is best seen on the skyline view. The other principal features are a lamellar-like pattern on slightly oblique lateral views, a smooth supra patellar erosion of the femur seen on the lateral view and cortical ridging of the lateral femoral condyle seen 'en face' on the AP projection. A possible mechanism to account for the radiological features is proposed. Anbarasu, A., Loughran, C. F. (2000). Clinical Radiology55, 767-769.

Aged↗
PubMed1999

Giant sigmoid diverticulum: a report of three cases.

The imaging appearances of three patients with a giant sigmoid diverticulum are described. The prominent feature was a large gaseous lucency noted in the lower abdomen on plain radiographs. Computed tomography (CT) was undertaken in two cases and in these a large gas filled collection was identified containing a small quantity of fluid. In the third case the collection was aspirated, contrast medium injected and a communication with the large bowel demonstrated. The condition is uncommon and needs to be distinguished from sigmoid and caecal volvulus.

Aged↗
PubMed1996

Crohn's disease, calculi and cancer: a report of two cases.

We describe two patients with long-standing Crohn's disease in which small bowel obstruction occurred secondary to a combination of small bowel enteroliths and stricture formation. In both patients some of the strictures were infiltrated by small bowel adenocarcinoma.

Adenocarcinoma↗
PubMed1994

Reporting of fracture radiographs by radiographers: the impact of a training programme.

In order to determine what influence training would have on their ability to interpret skeletal radiographs from the accident and emergency department, a 6 months training programme was established for three radiographers in various aspects of the radiology of orthopaedics and skeletal trauma. During the study the radiographers reported on radiographs from the accident and emergency department and each month an evaluation of their accuracy was undertaken. The overall radiographer error rate for fracture detection (false positive and false negative) declined during the training period. This was highly significant (p < 0.001). The sensitivity for fracture detection improved from 81.1% at the commencement of the trial to 95.9% at the end. This was also highly significant (p < 0.001). Radiographer specificity for the exclusion of fractures also improved from 94.4% during the first 2 months to 96.6% in the final 2 months, and this was also significant (p < 0.05). The overall error rate of two of the three radiographers improved significantly (p < 0.001) but for one radiographer the improvement did not reach a level of statistical significance. The difference in sensitivity for fracture detection at the commencement of the trial period between radiologist and radiographer was highly significant (p < 0.001), but there was no statistically significant difference during the last two months of the trial. The difference in specificity between radiologist and radiographer remained highly significant both at the beginning and the end of the trial (p < 0.001). Experienced radiographers who receive supplementary training in the radiology of skeletal trauma can significantly improve their diagnostic skills and can report such radiographs with a high degree of accuracy. A programme of training and certification of radiographers in fracture reporting could help alleviate the diagnostic radiologists' workload of plain film reporting.

Diagnostic Errors↗
PubMed1988

Uro-radiological manifestations of pancreatic carcinoma.

Two patients are described who suffered from pancreatic adenocarcinoma. These had extended to involve the urinary tract. One patient presented with haematuria from renal metastases. The other was diagnosed following the incidental discovery of a hydronephrosis by radionuclide bone scintigraphy. The radiological changes in these patients are described.

Adenocarcinoma↗
PubMed1986

A review of the plain abdominal radiograph in acute rupture of abdominal aortic aneurysms.

The abdominal radiographs of 31 patients, each with a surgically proven rupture of an abdominal aortic aneurysm, were reviewed retrospectively. The following changes were noted: calcification of the aneurysm in 65%, a soft tissue mass in 67%, complete loss of one or both psoas outlines in 75%, complete loss of one or both renal outlines in 78%, renal displacement in 25%, and properitoneal flank stripe changes in 19%. Unilateral loss of the subperitoneal fat line occurred in one patient. Loss of the psoas, renal and properitoneal-fat lines are indicative of a large retroperitoneal fluid collection. In patients with acute or subacute intra-abdominal symptomatology, it is important to examine the radiograph with specific attention directed at these retroperitoneal fat planes. The diagnosis of a ruptured aneurysm may be made in 90% of patients, particularly in the presence of a calcific aortic rim.

Acute Disease↗
PubMed1986

Clinical intravenous urography: comparative trial of ioxaglate and iopamidol.

A comparative trial of ioxaglate sodium meglumine and iopamidol in excretory urography was undertaken. The study failed to demonstrate any statistically significant differences between the two media in terms of urographic quality. Diagnostically adequate urograms were obtained in 92.6% of patients receiving ioxaglate and 89.6% of patients receiving iopamidol. There were no intermediate, major, or fatal reactions with either media. Minor reactions were slightly more common with ioxaglate. Both media are good, safe urographic agents, and either can be advocated when excretory urography with low-osmolar agents is indicated.

Adolescent↗
PubMed1983

Bone metastases from squamous-cell carcinoma of the larynx.

Four patients are described with distant bone metastases from primary squamous-cell carcinoma of the larynx. In one case the metastases were osteosclerotic, a previously unreported occurrence. The metastases were osteolytic in the other three patients. Bone metastases from laryngeal carcinoma are rare and associated with locally extensive tumours and a poor prognosis.

Aged↗