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Biomedical subjects

C Fetkenhour

Publications and source records attributed to C Fetkenhour.

3 recordsLinked to original sources

Ophthalmologic findings in acquired immune deficiency syndrome (AIDS).

Forty-one homosexually active men had ophthalmologic and immunologic evaluations. Four of eight with acquired immune deficiency syndrome (AIDS) had abnormal ocular findings that included cotton-wool spots, retinal hemorrhages, cytomegalovirus, retinitis and conjunctivitis due to cytomegalovirus, and keratoconjunctivitis sicca. The other four patients with AIDS and 33 homosexual male controls had normal ocular examinations. Patients with AIDS and abnormal eye findings had a notably lower total leukocyte count, absolute lymphocyte count, percentage T-helper lymphocytes, helper-suppressor lymphocyte ratio, hematocrit level, and platelet count than patients with AIDS and normal results on eye examination or controls. All patients with AIDS and abnormal eye examination results died; the four other patients with AIDS and normal eye findings remain alive. These observations suggest that ophthalmologic abnormalities are common in patients with AIDS, are associated with severe immunoregulatory abnormalities, and carry a poor prognosis.

Acquired Immunodeficiency Syndrome

Malignant melanoma of choroid in a case of nevus of Ota.

A white woman with unilateral nevus of Ota presented with visual loss and an intraocular mass resembling a choroidal melanoma. Indirect ophthalmoscopy, fluorescein angiography, ultrasonography, and radioactive phosphorus uptake corroborated the clinical impression and surgery was advised. Following enucleation, the specimen was examined with light microscopy, which revealed a mixed cell type malignant melanoma of the choroid. Electron microscopy disclosed the presence of premelanosomes in the episclera, indicating that the episcleral pigmentation is a result of melanocytic evolution. This paper represents the tenth report in the literature of choroidal melanoma occurring in a patient with nevus of Ota, and the first electron-microscopic study of an eye with this association of lesions.

Aged

Visual function after pan-retinal photocoagulation: a survey.

Thirty-five diabetic patients who had undergone pan-retinal photocoagulation were surveyed to determine the frequency and severity of visual difficulties they experience. Among the most frequent problems were difficulty adjusting to dim lighting, difficulty adjusting to bright lighting, and trouble in sorting dark colors. Judging distances, negotiating stairways, and avoiding obstacles were identified as having become more difficult since the laser treatment. According to a correlation analysis, the difficulties encountered in some important tasks, such as driving in the daytime, were highly related to visual acuity. However, many of the problems reported most frequently, and many of the problems whose frequency had increased the most since the laser therapy, were not related to acuity. Despite their many visual complaints, the patients expressed very positive attitudes toward the photocoagulation treatment.

Adaptation, Ocular