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Biomedical subjects

C Fiore

Publications and source records attributed to C Fiore.

At least 19 recordsLinked to original sources

Activating tasks for the study of visual-spatial attention in ADHD children: a cognitive anatomic approach.

The clinical label attention deficit hyperactivity disorder (ADHD) suggests that this syndrome is a disorder of attention. However, the presumed attentional deficits have not been linked either to specific cognitive operations or to specific neural systems. To provide this link, theories of the cognitive anatomy of attention were used to generate hypotheses about specific visual-spatial attentional deficits in children with ADHD. A cued reaction-time test was used to assess covert and overt shifts of attention theoretically linked to two neuroanatomically defined attentional systems in the posterior and anterior parts of the human brain. The early, posterior-based covert shift of attention was found to be normal in ADHD children, but a later, anterior-based overt shift of attention was abnormal as reflected by a significant lateral difference in reaction time. This was interpreted as a failure to sustain focused attention.

Analysis of Variance

[Bone choristoma of the bilateral choroid and asymmetric microphthalmia].

The authors report a case of associated bilateral asymmetrical microphthalmia and osseous choristoma of the choroid in a seventeen year old young woman. This association, to the author's knowledge, has not been previously reported in the literature. The bone choristoma was present in the eye's posterior poles and the clinical features were studied by electroretinography, fluorescein angiography, A-B scan ultrasonography, computerized axial tomography and nuclear magnetic resonance. The authors hypothesize that a choroid developmental tumor was produced by exposure to the rubella virus during embryonic life.

Adolescent

Associated retinitis pigmentosa and fundus flavimaculatus.

A family is described with 2 members, father and son, affected by associated retinitis pigmentosa and fundus flavimaculatus, whereas 1 other member had a combination of retinitis pigmentosa and unilateral central areolar atrophy, 1 member a fundus flavimaculatus with electroretinographic findings indicative of a subclinical form of retinitis pigmentosa and the last one with electroretinographic findings indicative of a subclinical form of retinitis pigmentosa.

Adult

[Chorioretinal changes in the course of sympathetic ophthalmia].

A case of sympathetic ophthalmitis is reported. A bull's eye chorioretinopathy was observed with electroretinographic changes (augmentation of latencies and disappearance of oscillatory potentials) which regressed in a short time. The authors believe that the retinal changes could be secondary to an autoimmunological reaction, responsible for the sympathetic ophthalmitis.

Adolescent

Recurring bilateral hypopyon in chronic myeloid leukemia in blastic transformation. A case report.

There have been many reports in the literature on keratohypopyon in acute leukemia. We report a case of a 40-year-old-man with chronic myeloid leukemia who developed bilateral, recurring kerato-hypopyon, the first manifestation of which appeared during intrathecal chemotherapeutic treatment just after an episode of leukemic meningiosis. There was no involvement of the CNS at the time of the relapse of kerato-hypopyon.

Adult

Gammaglobulins and immunocomplexes in aqueous humor and serum of patients with senile cataract.

The authors have measured the gammaglobulins and the immunocomplex levels (CIC) in aqueous humor and serum of 14 patients (3 males and 11 females) over 50 years old, who were affected by different types of cataract. Even if the authors have examined a limited number of samples, the results confirm the previous data which also showed very low levels of IgG, IgA, IgM, IgE, CIC in aqueous humor.

Aged

The effect of the epidermal growth factor (EGF) on the corneal epithelium in humans.

Epidermal growth factor (EGF) is a polypeptide hormone present in mammalian organs. In vivo, it shortens the time course of the corneal reepithelialization by stimulating a marked cell proliferation of the corneal epithelium. A further direct effect in vivo has been confirmed on human corneal epithelium and epidermis in culture. Tests in several nondystrophic diseases of the corneal epithelium confirmed the observations previously made in the rabbit that EGF accelerates the process of epithelial healing. The integrity of the corneal stroma is prejudicial for the maximum effect of the EGF, in the sense that the deeper the stroma is damaged, the less EGF acts. In herpetic lesions EGF is effective within 48 h only when the virus-affected area of the corneal epithelium has been scraped off. EGF is proposed as a new and efficacious agent for increasing the restorative process of the corneal epithelium in many nondystrophic diseases.

Adolescent

[Degenerative ocular retinal albinism in a girl ten years old (author's transl)].

Ocular albinism with myopia and impaired vision (R.E. 0.2; L.E. 0.6), but without nystagmus, were observed in a 10-year-old girl. The electrophysiological tests indicate, in addition, the presence of a tapetoretinal degeneration. It is assumed that the patient is carrier of two genes, a sex-linked one responsible for albinismus solum fundi and a second one of autosomal-recessive type, responsible for the tapetoretinal degenerartion.

Albinism

[Goldmann-Favre hyaloido-tapetoretinal degeneration].

In a sister and brother we found a case of vitreo-tapeto-retinal degeneration (macular retinoschisis, night-blindness, vitreous micro-fibrillose degeneration, abolished E.R.G., very pathological E.O.G.) and a "fruste" form of tapeto-retinal degeneration (De Lange's curve and flicker-E.R.G. both modified, E.R.G. subnormal and slight pathological changes in adaptometry). The father of these two patients suffered from tapeto-retinal degeneration which had caused complete blindness. Basing their suppositions on their personal experience and medical literature, the authors believe that the type of vitreo-retinal degeneration is best determined after examination of the mode of hereditary transmission. In the family which is presented, they believe that it is a form of Goldmann-Favre's disease with pseudo-dominance.

Adaptation, Ocular

[Value of functional and electrophysiological studies in amblyopia].

In a group of patients suffering from amblyopia, the authors confront the results after orthoptic treatment with data provided by functional and electrophysiological examination. In 37 patients the clinical diagnosis of functional amblyopia had been made, but in 8 of these cases complimentary functional and electrophysiological examinations showed organic perturbations. This explains the failure, in these cases, of the orthoptic treatment. In the remaining 29 patients, clinical forms of functional amblyopia were found. In this group, the authors studied 20 cases showing no improvement with treatment: in 15 out of the 20 the VERs were pathological. In the 9 remaining cases which have showed improvement the VER'S were never abnormal. VER study can be undertaken, without general anaesthesia, as from 3 to 4 years of age. The authors conclude that all clinical forms of amblyopia should undergo VER investigation: patients showing pathological changes should be excluded from orthoptic treatment, from which they have no possibility of deriving benefit.

Amblyopia

[Evoked visual potentials in tapeto-retinal degeneration].

A study of the behaviour of V.E.P. latencies and amplitudes in 247 eyes suffering from different clinical forms of chorio-retinal degenerations is presented. In 147 eyes the E.R.G. and the V.E.R. were simultaneously recorded, and this group was used for studying the relation ship between E.R.G., V.E.P. and visual acuity. The authors are of the opinion that the V.E.P., in that it investigates particularly the macular region, provides a clinical test of real interest in the prognosis of visual acuity in a known clinical context.

Choroid

[Genetic counseling in retinoblastoma].

The author reviews the literature about the inheritance of retinoblastoma and notes an increase of both the frequency of the affection and the chance of survival. He then estimates the genetic risks for the descendency in all cases of sporadic and familial retinoblastoma.

Chromosome Deletion