PubMed Health⌕ Search

Biomedical subjects

C Forbes

Publications and source records attributed to C Forbes.

51 records · Page 3Linked to original sources
PubMed1980

Sex-linked lethal mutations induced in Drosophila melanogaster by 7,12-dimethylbenz[a]anthracene.

One of the most potent carcinogens, 7,12-dimethylbenz[a]anthracene (DMBA), was tested for the induction of mutations in 2 strains of Drosophila melanogaster. Larvae were fed mixtures containing DMBA, peanut oil and solubilizing agents in darkness. After emergence the males were mated with Basc or FM7a females to test for sex-linked lethals. For Canton-S males, all DMBA treatments produced highly significant increases in mutation frequencies over controls. DMBA was slightly mutagenic for Oregon-R males.

9,10-Dimethyl-1,2-benzanthracene↗
PubMed1980

Self-perception of employed and unemployed haemophiliacs.

Semi-structured interviews concerning various aspects of mental health were carried out with 13 employed and 13 unemployed haemophiliacs 20-35 years old. Significant differences in patients' responses were related to their employment status and the degree of severity of haemophilia. Unemployed patients with milder forms of haemophilia appeared to be least adjusted and suffered most from psychosomatic symptoms.

Adult↗
PubMed1978

Haemophilia A home therapy in the United Kingdom 1975-6.

Data on home treatment for patients with haemophilia A (factor VIII deficient haemophilia) were compiled for 1975 and 1976 from questionnaires answered by directors of haemophilia centres throughout the United Kingdom. There were 48 haemophilia centres in 1975 and 71 in 1976. The number of patients on or in training for home treatment increased from 267 to 488 in the two years, and a further 241 haemophiliacs were considered suitable for home therapy by the end of 1976. Apart from a small (but increasing) number of haemophiliacs on prophylactic treatment, most patients were on low-dose (250-500 units) on-demand regimens, using a mean of 20 000 factor VIII units per patient per year in 1976. An estimated 55% of the blood product used for home therapy in the UK in 1976 was imported from commercial sources. Despite the fact that the numbers of patients on home treatment have increased, so that about 60% of the potential population were receiving or being considered for home treatment in 1976, inadequacies in the service still remain. In some centres follow-up is clearly inadequate; about 15% of patients still rely on cryoprecipitate; and too little money has been invested in making the NHS self-sufficient in factor VIII production.

Antibodies↗
PubMedDate not supplied

Integration of haemophilic boys into normal schools.

Advances in the medical treatment of haemophilia have made it possible for the majority of haemophilic children to attend ordinary rather than special schools. A survey carried out in the Glasgow and Edinburgh regions among families with haemophilic children and the schools which these children attend has drawn attention to certain implications of this new policy.

Absenteeism↗