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Biomedical subjects

C Formisano

Publications and source records attributed to C Formisano.

At least 19 recordsLinked to original sources
PubMed2000

Solitary necrotic nodule of the liver misinterpreted as malignant lesion: considerations on two cases.

In our experience, we document 2 cases of a rare and non-tumoral lesion of the liver misinterpreted as necrotic tumor: necrotic solitary nodule. In the first clinical case, ultrasound (US) showed a polylobated lesion (35 x 35 x 38 mm) at segment 8. Color-doppler identified a compression of celiac axis (Dunbar syndrome). Arteriography revealed a subtotal stenosis of celiac tripod soon after the emergence of the left gastric artery. FNAB-CT showed a highly cellulated tissue with a necrotic core surrounded by a fibersclerotic tissue. The patient underwent surgery: cholecystectomy and correction of Dunbar syndrome. US follow-up showed a progressive reduction in diameter of the lesion (24 x 25 x 25 mm at 24 months), suggesting in this case the role of ischemic injury in the pathogenesis of the lesion. In the second clinical case, a hypoechoic lesion (32 x 32 x 30 mm) of segment 6 as occasional US finding during the staging for prostate cancer was shown. FNAC-CT showed a positive result for necrotic cells. Surgical treatment consisted in a wide excision of the lesion. Histologically the lesion was solitary necrotic nodule. The diagnosis of this rare lesion is accidental. In accordance with the literature (50% of cases), we founded an associated tumor. Radiology doesn't differentiate solitary necrotic nodule and other solid lesions. Diagnosis is histological (in our second case, FNAC-CT misinterpreted the tumor as a malignant lesion, while histology showed the real nature of it).

Adult↗
PubMed2000

Laparotomic vs laparoscopic lap-band: 4-year results with early and intermediate complications.

BACKGROUND: Adjustable banding is safe, low invasive, and effective for losing weight. METHODS: 69 patients underwent this procedure by laparotomy or laparoscopy. RESULTS: Patients operated by laparotomy lost more weight than those operated by laparoscopy, but in 4 patients we were forced to re-operate in order to remove the band (3 pouch dilatations and 1 stomach slippage), and in 9 patients a ventral hernia appeared (5 patients repaired). In the laparoscopic cases there were 4 intra-operative gastric perforations, but all were repaired and the band placed at the same time (3 conversions to open), causing an increased post-operative hospital stay. There was a lower limb deep venous thromboembolism, which was followed by fatal pulmonary embolism (although the patient had been given heparin and had been treated with elastocompression and mobilization 2 hours after surgery). The band eroded in one patient. Weight losses in these morbidly obese patients were satisfactory at 2 years and maintained beyond 3 years. CONCLUSION: Laparoscopic adjustable banding is an efficient, generally safe procedure.

Adult↗
PubMed2000

Lymph node mapping and sentinel lymph node biopsy for evaluation of axillary lymph node status in early invasive breast cancer. Our experience.

The Authors show their preliminary experience with the sentinel lymph node biopsy (SLNB) in clinical early invasive breast cancer (T1N0). During a period of 15 months, forty-two patients were submitted to SLNB upon Tc99-colloid albumin injection and SLN identification by lymphoscintigraphy. The middle number of lymph nodes found in the SLNB was 1 (1-3), whereas the middle number of lymph nodes identified in level I/II ALND specimens was 15. The SLN was identified with success in all cases (100%). The axilla was positive for metastasis in 4/42 cases. The SLN was positive in all four cases in which nodal metastasis was identified. The negative predictive value of SLN was 100%. The SLN was the only site of metastasis in 3/4 cases. The SLN pathological status accurately reflected the lymphatic basin status, but further investigation is needed to define the optimal timing of colloid injection and method of examination of the SLN.

Adult↗
PubMed1989

Carcinoma following gastric surgery: a national survey.

Definitive results of a national survey on the incidence of carcinoma following gastric surgery are reported. Data concern 8427 cases of surgically treated gastric cancer. 558 were affected by carcinoma following gastric surgery and 471 of them were operated on, representing 5.59% of all gastric cancers (8427) submitted to surgery. The statistical analysis of results has pointed out the need for a close follow-up program in patients over 50 years, operated on for benign gastroduodenal disease, especially 10 years postoperatively and in case of pre-cancerous lesions.

Aged↗
PubMed1984

Short bowel syndrome: clinical manifestations following extensive intestinal by-pass.

A personal experience with 43 cases of end-to-side jejunoileal bypass is reported. Two major clinical entities appear to emerge from the present study and in accordance with data from the literature: liver failure and the so-called enteric disease from bypass. Such observations were confirmed by the results obtained from an experimental investigation on 96 Wistar rats. The fact that the intestinal bacterial contamination seems to be the common cause of both effects and complications of intestinal bypass should limit by itself possible further developments of the procedure.

Diarrhea↗
PubMed1983

A modified Payne technique with a personal antireflux valvular system in the surgical treatment of morbid obesity.

Reflux into the blind loop in end-to-side jejuno-ileal bypass is commonly considered the cause of weight loss failure, but the lower morbidity and mortality suggest that this procedure should be preferred to end-to-end bypass in the surgical treatment of morbid obesity, with the proper technical modifications to prevent the reflux. An antireflux single or double valvular system created 3-6 cm proximally to the anastomosis, with few introverting seroserous stitches, parallel and perpendicular to the ileal axis, is reported. This technique, as compared to others, is not time consuming, is easily feasible and does not interfere with the blind loop down-flow. Comparative clinical data and x-ray controls demonstrated the value of this procedure which is able to give excellent results in cases where other procedures (gastric operations, bilio-intestinal, bilio-pancreatic bypass etc.), are contraindicated.

Barium Sulfate↗