Biomedical subjects

C G Arcoleo

Publications and source records attributed to C G Arcoleo.

2 recordsLinked to original sources

PubMedDate not supplied

Blood lead stability.

Blood lead levels, the single most useful and authoritative index of lead toxicity, has heretofore been faulted for the following weaknesses: (1) it is too responsive to evanescent environmental changes, thereby putting its stability into question; (2) it does not provide sufficient insight into a total body burden; and (3) it may be normal at a time when toxicity is still occurring or has occurred recently. Each "weakness" is addressed herein, and hopefully, put into a useful perspective, i.e., at a clinical research and treatment level, none of the above is severe enough, if extant at all, to outweigh its manifold usefulness.

Analysis of Variance↗

PubMedDate not supplied

Chelation therapy in children as treatment of sequelae in severe lead toxicity.

Certain children who experience a toxic lead episode requiring hospitalization in infancy or early childhood will manifest central nervous system dysfunctions, including hyperactivity, as sequelae of this experience. In this study, findings indicate that persistent, higher-than-normal lead levels, dating back to the time of the initial toxicity, may well be a mechanism underlying some of these sequelae. Consequently, some part of these sequelae may be preventable and/or treatable.

Child↗