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Biomedical subjects

C G Costello

Publications and source records attributed to C G Costello.

At least 19 recordsLinked to original sources

Problems in recent tests of two cognitive theories of panic.

Four problems in five recent tests of two cognitive theories of panic are discussed: (a) the ambiguity and indistinguishability of the 'body sensations' and 'cognitions' concepts; (b) the uncertain meaning of 'meaningful relationships'; (c) problems arising from differences in Clark's (Behaviour Research and Therapy, 24, 461-470, 1986) theory and Goldstein and Chambless' (Behavior Therapy, 9, 47-59, 1978) theory; (d) the ambiguity of correlational data. Some desiderata for future research on these theories are proposed.

Adaptation, Psychological

Research on symptoms versus research on syndromes. Arguments in favour of allocating more research time to the study of symptoms.

Research on symptoms may often be more fruitful than research on syndromes because: (a) the validities of psychiatric diagnoses remain questionable; (b) interview assessments of a large number of symptoms are inadequate; (c) the diagnostic approach results in problems of misclassification and confounding; (d) the dimensional/categorical issue may be more readily resolved with research using a symptom approach; (e) useful animal models of symptoms are more likely to be developed than useful animal models of syndromes; and (f) symptoms may be better phenotypes than syndromes in genetic research.

Animals

Do confidants of depressed women provide less social support than confidants of nondepressed women?

The prediction was tested that during a simulated telephone conversation, the confidants of depressed women would provide less social support than the confidants of nondepressed psychiatric and nonpsychiatric control women. The coded speech of subjects and their confidants indicated that (a) confidants echoed the positive or negative valence of the statements made by subjects; (b) depressed women exhibited more depressotypic speech than women in both control groups; (c) confidants of depressed women also made more depressotypic statements, possibly due to the echoing phenomenon; (d) contrary to prediction, there were no significant group differences in the sequential dependencies of responses that confidants made to depressotypic or antidepressotypic subject statements; (e) contrary to prediction, the affect of depressed women's confidants was not more negative.

Adult

Primary and secondary depression: a review.

The literature on the distinction between primary and secondary depression is reviewed. The research data indicate that less severe, non life-threatening suicidal thoughts and behaviours occur more often in patients with secondary depression than in those with primary depression and that the prognosis for secondary depression after somatic forms of therapy is poorer than that for primary depression. The data also suggest that secondary depressives, unlike primary depressives, suffer from chronic dysphoria. It is concluded that, because the available evidence suggests that there are no qualitative differences between the episodes of primary and secondary depression, future research should concentrate on investigating the characteristics of different groups of patients with secondary depression rather than on comparisons between primary and secondary depression in general.

Depressive Disorder

The similarities and dissimilarities between community and clinic cases of depression.

It has been hypothesised that community cases of depression compared with clinic cases: (a) have fewer symptoms; (b) have milder symptoms; (c) have different symptoms; (d) are of shorter duration; (e) are less incapacitating; (f) are more environmentally and less biologically caused; and (g) respond better to psychological than pharmacological intervention. A review of the literature indicates that some of these hypotheses have not been tested, others have not been adequately tested, and none has been unequivocally confirmed. Further investigations of these important issues are required.

Alberta