Presentation of prostatic adenocarcinoma with cervical lymphadenopathy: two case reports and review of the literature.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to C G Gaches.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
We describe the effect of ranitidine in reducing mucus in urine in 8 patients with enterocystoplasty and present a simple technique for measuring the concentration of mucus in urine. After a 10-day course of ranitidine (300 mg daily in divided doses) the concentration of mucus had fallen significantly from an initial level of 1.38 +/- 0.18 to 0.39 +/- 0.04 mg/ml.
Clam enterocystoplasty has been used successfully in the treatment of refractory urge incontinence. We report 31 patients who underwent ileocystoplasty between 1982 and 1989. The majority of patients were pleased with the outcome of the operation. The main post-operative complication was voiding dysfunction due to relative bladder outflow obstruction. Urinary tract infection and mucus production were significant long-term problems.
Distigmine bromide (Ubretid) is a long-acting anticholinesterase which is thought to improve detrusor function, restoring normal voiding patterns which may have been disturbed by autonomic overactivity, particularly after surgery. Ninety-three patients entered a double-blind study of the effect of distigmine bromide versus placebo on voiding after prostatectomy. The results demonstrated that there was a trend towards improvement but no statistically significant increase in post-operative flow rates, in reduction in bladder volume, and in the incidence of re-catheterisation in the patients treated with distigmine bromide.
Blood loss during operation was measured in 106 patients undergoing transurethral resection of the prostate, using a colorimetric technique. The total blood loss was related to the length of operation and the weight of prostate resected. There was no relationship between blood pressure and the blood loss during operation. However there was a significant reduction in blood loss if the patient received a regional rather than a general anaesthetic. Blood loss was lower in those patients undergoing prostatectomy for carcinomatous disease.
Sixty patients with recurrent superficial bladder tumours (Ta or T1) entered an open controlled trial of single dose Adriamycin. After transurethral resection of tumor recurrences, patients were alternately allocated to the control group or to the Adriamycin group, who received an instillation of 50 mg of Adriamycin in 50 ml of saline for 30 min. Six months later all patients were readmitted for endoscopy. In the Adriamycin group significantly more patients showed a decrease in the number of recurrent papillomas (72%) than in the control group (39%). This study shows that the use of adjuvant chemotherapy in the form of single dose Adriamycin is effective in reducing tumour recurrence.
Verrucous carcinoma of the penis or 'Buschke-Löwenstein' tumour is a rare lesion. The condition may be mistaken for condyloma acuminatum or epidermoid carcinoma of the penis which carries a worse prognosis. The verrucous carcinoma once completely excised rarely recurs. All reports of recurrence were thought to be due to inadequate excision. Three cases of this tumour have presented to our department within the last 9 months and their presentation and clinical management will be outlined in this paper.
We have undertaken a detailed retrospective study of urinary calculi in the Bristol clinical area from 1950 to 1978. Most calculi in children are detected in the upper urinary tract and the majority are associated with urinary infection. There were two predominant aetiological groups. First the children under 5 years of age, usually male, with a Proteus infection and triple phosphate calculi of the staghorn type in the renal pelvis and calyces. Of the 7 children with a sterile urinary tract in this age group, 4 were discovered to have a metabolic cause for the their calculi. These included 2 patients with cystinuria, 1 with uric acid calculi secondary to the treatment of leukaemia and 1 baby with the adrenogenital syndrome. A second smaller group of children between 8 and 13 years of age presented with ureteric calculi due to calcium oxalate stones in a sterile urinary tract. In the first group the importance of Proteus infections of the urinary tract is emphasised, and possibility of an underlying metabolic abnormality is noted if the urine is sterile. The second group presenting with ureteric colic are no different from adults with "idiopathic" calcium oxalate stones.
Renal angiomyolipomata are rare hamartomatous tumours which usually occur unilaterally. A correct clinical diagnosis is often difficult and nephrectomy has been the outcome of treatment in most cases described. A rare case of bilateral renal angiomyolipomata is presented and the successful conservative surgical management discussed.
One hundred and nine male patients took part in a randomized trial of elective suprapubic or urethral catheterization in retention of urine. The self-retaining trocar suprapubic catheter proved safe and reliable in trained hands and its use was associated with a low incidence of side effects. The suprapubic catheter when used to allow continuous flow resection appeared to lead to decreased blood loss and reduced resection time. No decrease in urinary infection rate over the period of hospital stay was noted in the suprapubic group. The suprapubic catheter was more comfortable than the urethral and also allowed a trial of voiding prior to removal. Use of the suprapubic catheter was not associated with an increased hospital stay.
The advent of selective internal urethrotomy under direct vision has enabled precision endoscopic surgery to be undertaken on a wide range of urethral strictures. A multi-centre survey of 197 cases involving 322 urethrotomy procedures from 5 urological departments in England is reported. The overall results after a follow-up of up to 4 years suggest that there is no indication for further procedures currently existing in 160 (81%) of those cases subjected to selective internal urethrotomy. The additional injection of triamcinalone acetate into the strictured area prior to urethrotomy is recommended in resistant cases. The procedure of selective internal urethrotomy is, in our opinion; the best primary method for the treatment of urethral stricture, and it is hoped this will reduce the indications for anastomotic or substitution urethroplasty.