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Biomedical subjects

C G Kaplan

Publications and source records attributed to C G Kaplan.

6 recordsLinked to original sources
PubMed1989

Implantation site on a cellular leiomyoma: a light microscopic and immunohistochemical study.

A case of gestational implantation upon a submucosal cellular leiomyoma in a 43-year-old woman is presented. The resulting histologic picture resembled placental site trophoblastic tumor (PSTT). In immunoperoxidase studies, tumor cells were positive for desmin and vimentin and negative for human placental lactogen and human chorionic gonadotropin, thus supporting a smooth muscle origin. This case demonstrates an unusual histological picture occurring in a setting that might lead to diagnostic confusion and is one in which immunohistochemical evaluation proved to be of great utility.

Abortion, Incomplete↗
PubMed1985

Microglandular hyperplasia of the uterine cervix.

Forty-three cases of microglandular hyperplasia of the cervix seen during a 3.5-year period are reported. The series is unusual in that more than one-half of the patients had no history of oral contraceptive use and three patients were postmenopausal. Additionally, evidence of estrogenic stimulation was present in eight cases. The role of estrogens and progestogens in the development of microglandular hyperplasia is discussed. The authors consider microglandular hyperplasia to be an unusual and florid form of reserve cell hyperplasia with glandular differentiation.

Adult↗
PubMed1979

Cytogenetics of extragonadal tumors.

Tissue from six human extragonadal teratomas was obtained for cytogenetic study. These included two gluteal lesions in infant females, and one each of thyroid, mediastinal, sacral and gastric teratomas in males. Tissue culture characteristics indicated tumor growth. All tumors, except the mediastinal lesion showed the presumed karyotype of its host, XX or XY. The mediastinal mass was tetraploid XXYY and contained an X chromatin body and double Y bodies. Our data support the concept that extragonadal teratomas in males and females arise mitotically from diploid cells and are more similar to identical twins. No heterosexual (XX) tumors were seen in males which would be expected in parthenogenetic tumors. The sex chromatin positive tumors seen in earlier studies may have resulted from polyploidy. Thus, male and female extragonadal teratomas have a different origin from the postmeiotic ovarian teratomas.

Adult↗
PubMed1979

Intrauterine infections in nonhuman primates.

Gross and histologic examination of five nonhuman primate placentas revealed inflammatory processes, either of the ascending type, with chorioamnionitis and fetal vasculitis, or of the hematogenous type with villitis. These reactions were similar to those occurring in man, with known implications for perinatal outcome.

Animals↗
PubMedDate not supplied

"Chromatolytic" neurons in lateral geniculate body in Werdnig-Hoffmann disease.

In a case of Werdnig-Hoffmann disease, we have observed pathologic changes in the neuronal cell bodies of the lateral geniculate nucleus. These changes are similar to those seen in lower motor neurons and dorsal root ganglia. As the lateral geniculate nucleus and its projections are entirely central, this observation raises questions as to the possible etiologic role of root entry zone glial bundles in the evolution of neuronal alterations in severe spinal muscular atrophy.

Geniculate Bodies↗