PubMed HealthSearch

Biomedical subjects

C G Lacey

Publications and source records attributed to C G Lacey.

6 recordsLinked to original sources

Laparoscopy in the evaluation of gynecologic cancer.

Laparoscopy was used to evaluate 60 patients with a variety of known or suspected gynecologic neoplasms. Diagnostic laparoscopy was performed on 18 patients to confirm benign or malignant pelvic masses or to confirm peritoneal carcinomatosis. Ten of these 18 patients (56%) were found to have unresectable carcinomatosis or benign disease which did not require further surgery. Staging laparoscopy was performed on 13 patients of which 3 had clinically unsuspected intraperitoneal spread of their disease. Surveillance laparoscopy was performed on 29 patients to determine the remission, regression, or progression of their disease following treatment; 8 (27%) had progressive or unresectable persistent disease. Despite the fact that the study comprised a high-risk group of previously operated on or irradiated patients, there was only one major complication. There was, however, a 10% incidence of laparoscopic failure from inadequate visualization. Twenty-one of the study patients (35%) were spared a laparotomy by the use of laparoscopy. The findings of this investigation help to identify those gynecologic oncology patients who should benefit most from the use of laparoscopy as an adjunct to the diagnosis, staging, or surveillance of intraabdominal malignant tumors.

Abdominal Neoplasms

Laparoscopy. A clinical sign for intraperitoneal needle placement.

Experience with a new clinical sign for proper Verres needle placement is reported. Although the use of one or more tests to confirm accurate needle position have become standard, most complications associated with laparoscopy still result from inaccurate or extraperitoneal needle placement. This new sign, when present, has proven completely reliable and should aid laparoscopists in reducing the incidence of needle complications.

Female

Clostridium perfringens infection complicating chemotherapy for choriocarcinoma.

A case of Clostridium perfringens sepsis and gas gangrene complicating chemotherapy for gestational choriocarcinoma is reported. The infection was eradicated using antibiotics, surgery, and hyperbaric oxygen therapy. The pathophysiology, diagnosis, and treatment of this unusual but often lethal complication are reviewed.

Anti-Bacterial Agents